Estimating genetic ancestry proportions from faces.

Estimating genetic ancestry proportions from faces.
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估计面部的遗传祖先比例。

DOI:
10.1371/journal.pone.0004460
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发表时间:
2009
期刊:
影响因子:
3.7
通讯作者:
Shriver MD
Shriver MD
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Klimentidis YC;Shriver MD

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种族可以是人们识别自己和他人的一种手段。这种类型的认同介导了许多种社会互动,并可能反映了人类对长期群体生活的适应。最近在美国来自不同大陆的群体之间的混合物,以及历史上对这些群体成员之间表型差异的强烈强调,提供了一个机会来检查基于遗传标记的群体成员资格估计和基于视觉的面部特征估计之间的一致性程度。我们首先测量了美洲原住民,欧洲人,非洲人和东亚人的遗传混合物的程度,在14个自我确定的西班牙裔个体的样本中,选择覆盖广泛的美洲原住民和欧洲人的遗传混合物的比例。我们向生活在新墨西哥州的241名受试者展示了14名受试者的正面和侧面照片,并要求他们估计每个受试者的NA混合程度。我们根据观察者和遗传估计值之间的差异的汇总测量来评估每个观察者的总体一致性。我们发现,观察员达到了显着更高的一致性程度比预期的机会,一致性的程度以及估计的差异的方向不同的基础上观察员的种族,但不是观察员的年龄或性别。这项研究强调了身体外观和种族遗传指标之间潜在的高度不一致,以及种族归属感是如何根据具体情况而定的。我们将我们的研究结果与以前的研究结果进行比较,并讨论其影响。
Ethnicity can be a means by which people identify themselves and others. This type of identification mediates many kinds of social interactions and may reflect adaptations to a long history of group living in humans. Recent admixture in the US between groups from different continents, and the historically strong emphasis on phenotypic differences between members of these groups, presents an opportunity to examine the degree of concordance between estimates of group membership based on genetic markers and on visually-based estimates of facial features. We first measured the degree of Native American, European, African and East Asian genetic admixture in a sample of 14 self-identified Hispanic individuals, chosen to cover a broad range of Native American and European genetic admixture proportions. We showed frontal and side-view photographs of the 14 individuals to 241 subjects living in New Mexico, and asked them to estimate the degree of NA admixture for each individual. We assess the overall concordance for each observer based on an aggregated measure of the difference between the observer and the genetic estimates. We find that observers reach a significantly higher degree of concordance than expected by chance, and that the degree of concordance as well as the direction of the discrepancy in estimates differs based on the ethnicity of the observer, but not on the observers' age or sex. This study highlights the potentially high degree of discordance between physical appearance and genetic measures of ethnicity, as well as how perceptions of ethnic affiliation are context-specific. We compare our findings to those of previous studies and discuss their implications.
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