Specimens for Drugs-of-Abuse Testing
Specimens for Drugs-of-Abuse Testing
复制标题
滥用药物测试样本
DOI：
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复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
L. Kadehjian
中科院分区：
文献类型：
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作者：
L. Kadehjian
已利用各种各样的体液标本来分析是否存在滥用药物。尿液一直是并且仍然是用于药物滥用常规检测的最广泛的体液标本，但一些替代标本正在确立其适用于药物检测的地位。头发、汗液和口服液已经达到了足够的科学可信度，可以考虑在联邦监管的工作场所药物测试项目中使用。每个样本都提供了关于使用时间和程度以及损伤可能性的不同信息。其中一些标本（例如尿液和口腔液）甚至可以用简单的现场非仪器检测设备以及通过标准实验室方法进行分析。这些药物检测工具，作为识别药物使用的客观信息，已被证明在解决我们社会持续的药物滥用挑战方面非常有用。本章回顾了使用这些不同的体液标本进行药物滥用测试，解决了标本收集和处理的便利性、分析方法的便利性和准确性、对结果进行合理解释的能力以及最终的法律可辩护性之间的平衡。
A wide variety of body fluid specimens have been utilized for analysis for the presence of drugs of abuse. Urine has been and remains the most widely used body fluid specimen for routine testing for drugs of abuse, but several alternative specimens are establishing their place as suitable for drug testing. Hair, sweat, and oral fluid have reached a sufficient level of scientific credibility to be considered for use in the federally regulated workplace drug-testing programs. Each specimen provides different information about time and extent of use and likelihood of impairment. Some of these specimens (e.g., urine and oral fluid) can even be analyzed with simple on-site, noninstrumented testing devices, as well as through standard laboratory methods. These drugtesting tools, as objective pieces of information identifying drug use, have proven highly useful in addressing our society’s ongoing substance abuse challenges. This chapter reviews the use of these various body fluid specimens for drugs-of-abuse testing, addressing the balances between ease of specimen collection and handling, the ease and accuracy of analytical methods, the capability for sound interpretation of results, and, ultimately, legal defensibility.
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DOI：
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发表时间：
1996-04
期刊：
Drug metabolism and disposition: the biological fate of chemicals
影响因子：
--
作者：
S. Gygi;R. Joseph;E. Cone;D. Wilkins;D. Rollins
通讯作者：
S. Gygi;R. Joseph;E. Cone;D. Wilkins;D. Rollins
胎儿可卡因暴露：胎脂分析。
影响因子：
2.5
作者：
Moore,C;Dempsey,D;Deitermann,D;Lewis,D;Leikin,J
通讯作者：
Leikin,J
影响因子：
2.5
作者：
Gary L. Henderson;M. Harkey;Chihong Zhou;Reese T. Jones;Peyton Jacob
通讯作者：
Gary L. Henderson;M. Harkey;Chihong Zhou;Reese T. Jones;Peyton Jacob
检测母乳中的可卡因及其代谢物。
影响因子：
1.6
作者：
Winecker,RE;Goldberger,BA;Tebbett,IR;Behnke,M;Eyler,FD;Karlix,JL;Wobie,K;Conlon,M;Phillips,D;Bertholf,RL
通讯作者：
Bertholf,RL