MicroRNAs in the thyroid.
MicroRNAs in the thyroid.
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DOI:
10.1016/j.beem.2016.10.001
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发表时间:
2016-10
期刊:
影响因子:
--
通讯作者:
Kebebew E
中科院分区:
文献类型:
--
作者:
Boufraqech M;Klubo-Gwiezdzinska J;Kebebew E
The microRNAs (miRNAs) are small non-coding RNA comprising approximately 19–25 nucleotides. miRNAs can act as tumour suppressors or oncogenes, and aberrant expression of miRNAs has been reported in several human cancers and has been associated with cancer initiation and progression. Recent evidence suggests that miRNAs play a major role in thyroid carcinogenesis. In this review, we summarize the role of miRNAs in thyroid cancer and describe the oncogenic or tumour suppressor function of miRNAs as well as their clinical utility as prognostic or diagnostic markers in thyroid cancer.
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DOI:
10.1158/1541-7786.mcr-14-0158-t
发表时间:
2014-07
期刊:
Molecular cancer research : MCR
影响因子:
--
作者:
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通讯作者:
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影响因子:
21.3
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