H-DBAS: alternative splicing database of completely sequenced and manually annotated full-length cDNAs based on H-Invitational.
H-DBAS: alternative splicing database of completely sequenced and manually annotated full-length cDNAs based on H-Invitational.
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DOI：
10.1093/nar/gkl854
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
Imanishi, Tadashi
中科院分区：
文献类型：
--
作者：
Takeda, Jun-ichi;Suzuki, Yutaka;Nakao, Mitsuteru;Kuroda, Tsuyoshi;Sugano, Sumio;Gojobori, Takashi;Imanishi, Tadashi
选择性剪接的人类转录组数据库（H-DBAS）是一个专门的选择性剪接人类转录本数据库。在这个数据库中，每个选择性剪接（AS）变体对应于一个完整的测序和仔细注释的人类全长cDNA，其中一个收集的H-邀请人类转录组注释会议。H-DBAS共包含11744个位点的38664个代表性的选择性剪接变异体（RASV）。这些数据可以通过AS的各种特征来检索，这些特征根据人工注释进行注释，例如通过AS的模式，从而引起编码氨基酸和受影响蛋白质基序的改变，GO术语，预测的亚细胞定位信号和跨膜结构域。该数据库还记录了最近发现的非常复杂的AS模式，其中两个不同的基因似乎是桥接的，嵌套的或退化的（多个CDS）：在所有三种情况下，完全不相关的蛋白质由一个单一的基因座编码。通过使用AS Viewer，可以在全长cDNA的背景下分析每个AS事件，使用户能够经验性地理解AS事件与编码的氨基酸序列中随之发生的变化以及各种受影响的蛋白质基序之间的关系。H-DBAS可访问。
The Human-transcriptome DataBase for Alternative Splicing (H-DBAS) is a specialized database of alternatively spliced human transcripts. In this database, each of the alternative splicing (AS) variants corresponds to a completely sequenced and carefully annotated human full-length cDNA, one of those collected for the H-Invitational human-transcriptome annotation meeting. H-DBAS contains 38 664 representative alternative splicing variants (RASVs) in 11 744 loci, in total. The data is retrievable by various features of AS, which were annotated according to manual annotations, such as by patterns of ASs, consequently invoked alternations in the encoded amino acids and affected protein motifs, GO terms, predicted subcellular localization signals and transmembrane domains. The database also records recently identified very complex patterns of AS, in which two distinct genes seemed to be bridged, nested or degenerated (multiple CDS): in all three cases, completely unrelated proteins are encoded by a single locus. By using AS Viewer, each AS event can be analyzed in the context of full-length cDNAs, enabling the user's empirical understanding of the relation between AS event and the consequent alternations in the encoded amino acid sequences together with various kinds of affected protein motifs. H-DBAS is accessible at .
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影响因子：
9.8
作者：
Imanishi T;Itoh T;Suzuki Y;O'Donovan C;Fukuchi S;Koyanagi KO;Barrero RA;Tamura T;Yamaguchi-Kabata Y;Tanino M;Yura K;Miyazaki S;Ikeo K;Homma K;Kasprzyk A;Nishikawa T;Hirakawa M;Thierry-Mieg J;Thierry-Mieg D;Ashurst J;Jia L;Nakao M;Thomas MA;Mulder N;Karavidopoulou Y;Jin L;Kim S;Yasuda T;Lenhard B;Eveno E;Suzuki Y;Yamasaki C;Takeda J;Gough C;Hilton P;Fujii Y;Sakai H;Tanaka S;Amid C;Bellgard M;Bonaldo Mde F;Bono H;Bromberg SK;Brookes AJ;Bruford E;Carninci P;Chelala C;Couillault C;de Souza SJ;Debily MA;Devignes MD;Dubchak I;Endo T;Estreicher A;Eyras E;Fukami-Kobayashi K;Gopinath GR;Graudens E;Hahn Y;Han M;Han ZG;Hanada K;Hanaoka H;Harada E;Hashimoto K;Hinz U;Hirai M;Hishiki T;Hopkinson I;Imbeaud S;Inoko H;Kanapin A;Kaneko Y;Kasukawa T;Kelso J;Kersey P;Kikuno R;Kimura K;Korn B;Kuryshev V;Makalowska I;Makino T;Mano S;Mariage-Samson R;Mashima J;Matsuda H;Mewes HW;Minoshima S;Nagai K;Nagasaki H;Nagata N;Nigam R;Ogasawara O;Ohara O;Ohtsubo M;Okada N;Okido T;Oota S;Ota M;Ota T;Otsuki T;Piatier-Tonneau D;Poustka A;Ren SX;Saitou N;Sakai K;Sakamoto S;Sakate R;Schupp I;Servant F;Sherry S;Shiba R;Shimizu N;Shimoyama M;Simpson AJ;Soares B;Steward C;Suwa M;Suzuki M;Takahashi A;Tamiya G;Tanaka H;Taylor T;Terwilliger JD;Unneberg P;Veeramachaneni V;Watanabe S;Wilming L;Yasuda N;Yoo HS;Stodolsky M;Makalowski W;Go M;Nakai K;Takagi T;Kanehisa M;Sakaki Y;Quackenbush J;Okazaki Y;Hayashizaki Y;Hide W;Chakraborty R;Nishikawa K;Sugawara H;Tateno Y;Chen Z;Oishi M;Tonellato P;Apweiler R;Okubo K;Wagner L;Wiemann S;Strausberg RL;Isogai T;Auffray C;Nomura N;Gojobori T;Sugano S
通讯作者：
Sugano S
影响因子：
14.9
作者：
Nakao, M;Barrero, RA;Nakai, K
通讯作者：
Nakai, K
影响因子：
14.9
作者：
Lee, C;Atanelov, L;Xing, Y
通讯作者：
Xing, Y
影响因子：
7
作者：
Kimura, K;Wakamatsu, A;Sugano, S
通讯作者：
Sugano, S
影响因子：
14.9
作者：
Takeda, Jun-ichi;Suzuki, Yutaka;Imanishi, Tadashi
通讯作者：
Imanishi, Tadashi