Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes.
Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes.
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人载脂蛋白 CIII 基因以及 apo AI 和 apo CIII 基因之间的基因间区域的分离和序列分析。
DOI：
10.1089/dna.1.1984.3.449
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
J. Seilhamer
中科院分区：
文献类型：
--
作者：
A. Protter;B. Levy;J. Miller;G. Bencen;T. White;J. Seilhamer
我们已经分离并表征了人类载脂蛋白CIII的基因，这是富含甘油三酯的脂蛋白的主要成分。对该基因的完整DNA序列测定发现，编码序列被3个内含子中断，它们分别位于5'非编码区、信号序列编码区和成熟血浆蛋白编码区。我们分析了载脂蛋白CIII基因的结构，并将其与载脂蛋白AI基因进行了比较。此外，我们给出了位于载脂蛋白AI和载脂蛋白CIII基因之间的基因间区域的DNA序列。
We have isolated and characterized the gene for human apolipoprotein CIII, a major component of the triglyceride-rich lipoproteins. Determination of the complete DNA sequence of this gene revealed that the coding sequence is interrupted by three introns, which occur in the 5' noncoding region, in the region encoding the signal sequence and in the region coding for the mature plasma protein, respectively. We present an analysis of the structure of the apo CIII gene and compare it to the gene for apolipoprotein AI. In addition, we present the DNA sequence of the intergenic region lying between the apo AI and the apo CIII genes.
影响因子：
5.6
作者：
DEININGER, PL;JOLLY, DJ;SCHMID, CW
通讯作者：
SCHMID, CW