Random forests for genomic data analysis.
Random forests for genomic data analysis.
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DOI:
10.1016/j.ygeno.2012.04.003
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发表时间:
2012-06
期刊:
影响因子:
4.4
通讯作者:
Ishwaran, Hemant
中科院分区:
文献类型:
--
作者:
Chen, Xi;Ishwaran, Hemant
关键词:
Random forests (RF) is a popular tree-based ensemble machine learning tool that is highly data adaptive, applies to “large p, small n” problems, and is able to account for correlation as well as interactions among features. This makes RF particularly appealing for high-dimensional genomic data analysis. In this article, we systematically review the applications and recent progresses of RF for genomic data, including prediction and classification, variable selection, pathway analysis, genetic association and epistasis detection, and unsupervised learning.
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DOI:
10.1038/nrg2579
发表时间:
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期刊:
Nature reviews. Genetics
影响因子:
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通讯作者:
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