Recent progress in the study of brown adipose tissue.
Recent progress in the study of brown adipose tissue.
复制标题
棕色脂肪组织研究最新进展
DOI：
10.1186/2045-3701-1-35
复制
发表时间：
2011-10-28
影响因子：
7.5
通讯作者：
Ying H
中科院分区：
文献类型：
--
作者：
Yao X;Shan S;Zhang Y;Ying H
Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat. It is held that in mammals, long-term surplus food intake results in energy storage in the form of triglyceride and may eventually lead to obesity. Stimulating energy-dissipating function of brown adipose tissue in human body may counteract fat accumulation. In order to utilize brown adipose tissue as a therapeutic target, the mechanisms underlying brown adipocyte differentiation and function should be better elucidated. Here we review the molecular mechanisms involved in brown adipose tissue development and thermogenesis, and share our thoughts on current challenges and possible future therapeutic approaches.
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DOI：
10.1097/med.0b013e328337a81f
发表时间：
2010-04
期刊：
Current opinion in endocrinology, diabetes, and obesity
影响因子：
--
作者：
Cypess AM;Kahn CR
通讯作者：
Kahn CR
影响因子：
5.3
作者：
Kang, S;Bajnok, L;MacDougald, OA
通讯作者：
MacDougald, OA
影响因子：
10.5
作者：
Kajimura, Shingo;Seale, Patrick;Spiegelman, Bruce M.
通讯作者：
Spiegelman, Bruce M.
影响因子：
64.5
作者：
Lin, JD;Wu, PH;Spiegelman, BM
通讯作者：
Spiegelman, BM
DOI：
10.1073/pnas.0301964101
发表时间：
2004-03-23
影响因子：
11.1
作者：
Hansen, JB;Jorgensen, C;Kristiansen, K
通讯作者：
Kristiansen, K