Microbiota regulation of viral infections through interferon signaling.
Microbiota regulation of viral infections through interferon signaling.
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DOI：
10.1016/j.tim.2022.01.007
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发表时间：
2022-08
影响因子：
15.9
通讯作者：
Harris, Vanessa C.
中科院分区：
文献类型：
--
作者：
Wirusanti, Nurul I.;Baldridge, Megan T.;Harris, Vanessa C.
The interferon (IFN) response is the major early innate immune response against invading viral pathogens and is even capable of mediating sterilizing antiviral immunity without the support of the adaptive immune system. Cumulative evidence suggests that the gut microbiota can modulate IFN responses, indirectly determining virological outcomes. This review outlines our current knowledge of the interactions between the gut microbiota and IFN responses and dissects the different mechanisms by which the gut microbiota may alter IFN expression to diverse viral infections. This knowledge offers a basis for translating experimental evidence from animal studies into the human context and identifies avenues for leveraging the gut microbiota–IFN–virus axis to improve control of viral infections and performance of viral vaccines.
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影响因子：
11.1
作者：
Deleu S;Machiels K;Raes J;Verbeke K;Vermeire S
通讯作者：
Vermeire S
DOI：
10.1016/s2213-2600(20)30566-x
发表时间：
2021-05
期刊：
The Lancet. Respiratory medicine
影响因子：
--
作者：
Feld JJ;Kandel C;Biondi MJ;Kozak RA;Zahoor MA;Lemieux C;Borgia SM;Boggild AK;Powis J;McCready J;Tan DHS;Chan T;Coburn B;Kumar D;Humar A;Chan A;O'Neil B;Noureldin S;Booth J;Hong R;Smookler D;Aleyadeh W;Patel A;Barber B;Casey J;Hiebert R;Mistry H;Choong I;Hislop C;Santer DM;Lorne Tyrrell D;Glenn JS;Gehring AJ;Janssen HLA;Hansen BE
通讯作者：
Hansen BE
影响因子：
16.6
作者：
Antunes, Krist Helen;Fachi, Jose Luis;Duarte de Souza, Ana Paula
通讯作者：
Duarte de Souza, Ana Paula
一项针对Lopinavir/Ritonavir，Lopinavir/Ritonavir Plus IFN-β-1A和羟基氯喹对Covid-19患者的开放标签随机对照试验。
DOI：
10.1016/j.cmi.2021.05.020
发表时间：
2021-12
期刊：
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子：
--
作者：
Ader F;Peiffer-Smadja N;Poissy J;Bouscambert-Duchamp M;Belhadi D;Diallo A;Delmas C;Saillard J;Dechanet A;Mercier N;Dupont A;Alfaiate T;Lescure FX;Raffi F;Goehringer F;Kimmoun A;Jaureguiberry S;Reignier J;Nseir S;Danion F;Clere-Jehl R;Bouiller K;Navellou JC;Tolsma V;Cabié A;Dubost C;Courjon J;Leroy S;Mootien J;Gaci R;Mourvillier B;Faure E;Pourcher V;Gallien S;Launay O;Lacombe K;Lanoix JP;Makinson A;Martin-Blondel G;Bouadma L;Botelho-Nevers E;Gagneux-Brunon A;Epaulard O;Piroth L;Wallet F;Richard JC;Reuter J;Staub T;Lina B;Noret M;Andrejak C;Lê MP;Peytavin G;Hites M;Costagliola D;Yazdanpanah Y;Burdet C;Mentré F;DisCoVeRy study group
通讯作者：
DisCoVeRy study group
DOI：
10.1126/science.abc6261
发表时间：
2020-09-04
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Arunachalam PS;Wimmers F;Mok CKP;Perera RAPM;Scott M;Hagan T;Sigal N;Feng Y;Bristow L;Tak-Yin Tsang O;Wagh D;Coller J;Pellegrini KL;Kazmin D;Alaaeddine G;Leung WS;Chan JMC;Chik TSH;Choi CYC;Huerta C;Paine McCullough M;Lv H;Anderson E;Edupuganti S;Upadhyay AA;Bosinger SE;Maecker HT;Khatri P;Rouphael N;Peiris M;Pulendran B
通讯作者：
Pulendran B