Human Urine as a Noninvasive Source of Kidney Cells.

Human Urine as a Noninvasive Source of Kidney Cells.
复制标题

DOI:
10.1155/2015/362562
复制
发表时间:
2015
影响因子:
4.3
通讯作者:
Levtchenko E
Levtchenko E
中科院分区:
医学3区
文献类型:
--
作者:
Oliveira Arcolino F;Tort Piella A;Papadimitriou E;Bussolati B;Antonie DJ;Murray P;van den Heuvel L;Levtchenko E

文献摘要

参考文献

被引文献

相似文献

尿液代表了患者特异性肾细胞的无限来源,可以非侵入性地收获。尿源性足细胞和近端小管细胞已被用于研究疾病机制和筛选各种人类肾脏疾病的新型药物疗法。相反,尿肾干/祖细胞和细胞外囊泡可能有希望用于肾损伤的治疗。尿液作为活细胞来源的最大优点是易于收集和不太复杂的伦理问题。然而,在临床使用尿来源的肾祖细胞之前,仍必须进行广泛的表征和体内研究。
Urine represents an unlimited source of patient-specific kidney cells that can be harvested noninvasively. Urine derived podocytes and proximal tubule cells have been used to study disease mechanisms and to screen for novel drug therapies in a variety of human kidney disorders. The urinary kidney stem/progenitor cells and extracellular vesicles, instead, might be promising for therapeutic treatments of kidney injury. The greatest advantages of urine as a source of viable cells are the easy collection and less complicated ethical issues. However, extensive characterization and in vivo studies still have to be performed before the clinical use of urine-derived kidney progenitors.
DOI: 10.1371/journal.pone.0104490
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Dimuccio V;Ranghino A;Praticò Barbato L;Fop F;Biancone L;Camussi G;Bussolati B
通讯作者: Bussolati B
DOI: 10.1152/ajprenal.00184.2011
发表时间: 2012-01-01
影响因子: 4.2
作者:
Bussolati, Benedetta;Moggio, Aldo;Camussi, Giovanni
通讯作者: Camussi, Giovanni
DOI: 10.1371/journal.pone.0033115
发表时间: 2012
期刊: PloS one
影响因子: 3.7
作者:
Bruno S;Grange C;Collino F;Deregibus MC;Cantaluppi V;Biancone L;Tetta C;Camussi G
通讯作者: Camussi G
DOI: 10.1152/ajprenal.00532.2013
发表时间: 2014-05-01
影响因子: 4.2
作者:
Dobrinskikh, Evgenia;Okamura, Kayo;Blaine, Judith
通讯作者: Blaine, Judith
DOI: 10.1152/ajprenal.00272.2006
发表时间: 2007-02-01
影响因子: 4.2
作者:
Eyre, Jeanette;Ioannou, Kyriakos;Topham, Peter S.
通讯作者: Topham, Peter S.