Coronary Microvascular Dysfunction in Patients With Systemic Lupus Erythematosus and Chest Pain.

Coronary Microvascular Dysfunction in Patients With Systemic Lupus Erythematosus and Chest Pain.
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DOI:
10.3389/fcvm.2022.867155
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发表时间:
2022
影响因子:
3.6
通讯作者:
--
中科院分区:
医学3区
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--
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Chest pain is a common symptom in patients with systemic lupus erythematosus, an autoimmune disease that is associated with increased cardiovascular morbidity and mortality. While chest pain mechanisms can be multifactorial and often attributed to non-coronary or non-cardiac cardiac etiologies, emerging evidence suggests that ischemia with no obstructive coronary arteries (INOCA) is a prevalent condition in patients with chest pain and no obstructive coronary artery disease. Coronary microvascular dysfunction is reported in approximately half of SLE patients with suspected INOCA. In this mini review, we highlight the cardiovascular risk assessment, mechanisms of INOCA, and diagnostic approach for patients with SLE and suspected CMD.
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