Human Immunodeficiency Virus/AIDS in the Era of Coronavirus Disease 2019: A Juxtaposition of 2 Pandemics.

Human Immunodeficiency Virus/AIDS in the Era of Coronavirus Disease 2019: A Juxtaposition of 2 Pandemics.
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DOI:
10.1093/infdis/jiab114
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发表时间:
2021-11-16
期刊:
The Journal of infectious diseases
影响因子:
--
通讯作者:
Fauci AS
Fauci AS
中科院分区:
其他
文献类型:
--
作者:
Eisinger RW;Lerner AM;Fauci AS

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2019年冠状病毒病(COVID-19)大流行对人类免疫缺陷病毒(HIV)感染者产生了重大影响,干扰了艾滋病毒预防、治疗和护理的关键卫生服务。虽然艾滋病毒感染者有多种特征,COVID-19的影响可能各不相同,但艾滋病毒感染者的COVID-19严重程度与合并症的存在密切相关,合并症会增加COVID-19患者在没有艾滋病毒的情况下患严重疾病的风险。有效应对艾滋病毒和COVID-19大流行病的并发症需要科学家,行业和社区合作伙伴的新型协调和合作全球努力,以加速基础和临床研究,以及实施科学,以在现实世界中迅速实施循证干预措施。我们迫切需要加快开发和临床评估预防和治疗对策,以缓解艾滋病毒和COVID-19大流行病的并存。COVID-19和艾滋病毒/艾滋病同时流行,给全球带来了前所未有的社会、经济和公共卫生挑战。要有效应对这两种流行病,就需要作出新的协调和合作的全球努力,加快生物医学研究和实施科学,以迅速实施循证干预措施。
The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted persons with human immunodeficiency virus (HIV), interfering with critical health services for HIV prevention, treatment, and care. While there are multiple profiles of persons living with HIV and the impact of COVID-19 may differ for each, the severity of COVID-19 in persons with HIV is related strongly to the presence of comorbidities that increase the risk of severe disease in COVID-19 patients in the absence of HIV. An effective response to the juxtaposition of the HIV and COVID-19 pandemics requires a novel coordinated and collaborative global effort of scientists, industry, and community partners to accelerate basic and clinical research, as well as implementation science to operationalize evidence-based interventions expeditiously in real-world settings. Accelerated development and clinical evaluation of prevention and treatment countermeasures are urgently needed to mitigate the juxtaposition of the HIV and COVID-19 pandemics. Concurrent COVID-19 and HIV/AIDS pandemics pose unprecedented societal, economic, and public health challenges worldwide. Effective responses to these dual pandemics require a novel coordinated and collaborative global effort to accelerate biomedical research and implementation science to operationalize evidence-based interventions expeditiously.
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