Fluid attenuated inversion recovery (FLAIR) MRI at 7.0 Tesla: comparison with 1.5 and 3.0 Tesla.
Fluid attenuated inversion recovery (FLAIR) MRI at 7.0 Tesla: comparison with 1.5 and 3.0 Tesla.
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DOI：
10.1007/s00330-009-1620-2
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发表时间：
2010-04
影响因子：
5.9
通讯作者：
Luijten PR
中科院分区：
文献类型：
--
作者：
Zwanenburg JJ;Hendrikse J;Visser F;Takahara T;Luijten PR
评估三种场强下的液体衰减反转恢复（FLAIR）磁共振成像（MRI）的信噪比（SNR）、对比度和信号均匀性，以确定超高场强（7 T）下FLAIR的潜在增益和当前挑战。5名健康志愿者（年龄24 ± 4岁，4名男性）在1.5T、3T和7T下获得FLAIR图像。评价正常脑结构的图像均匀性和可见性。在不受发射场不均匀性影响的区域测量灰质（GM）、白色质（WM）和脑脊液（CSF）的SNR。与1.5T（GM 30 ± 3，WM 22 ± 2）和3T（GM 62 ± 7，WM 44 ± 4）相比，7T（GM 168 ± 15，WM 125 ± 11）下的SNR（平均值± SD）略高于比例增加。7T时GM和WM的相对对比度（1.35 ± 0.07）略低于3T（1.42 ± 0.14）或1.5T（1.37 ± 0.07）。在7T下，几个主要的纤维束变得可见。偶然观察到的一处白色病变在所有场强下均清晰可见。图像均匀性仍然具有挑战性，应通过未来的技术发展加以改善。FLAIR成像在7 T产生高SNR，与更好的对比度为WM亚结构和含铁基底神经节，并具有良好的显着性的WM病变的潜力。
To assess fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) at three field strengths, regarding signal-to-noise ratio (SNR), contrast and signal homogeneity, in order to determine the potential gain and current challenges of FLAIR at ultra-high field strength (7 T). FLAIR images of five healthy volunteers (age 24 ± 4 years, 4 male) were acquired at 1.5 T, 3 T and 7 T. Image homogeneity and visibility of normal brain structures were evaluated. SNR of grey matter (GM), white matter (WM) and cerebrospinal fluid (CSF) were measured in regions not affected by transmit field heterogeneity. The SNR (mean ± SD) at 7 T (GM 168 ± 15, WM 125 ± 11) increased slightly more than proportionally, compared with at 1.5 T (GM 30 ± 3, WM 22 ± 2) and 3 T (GM 62 ± 7, WM 44 ± 4). Relative contrast between GM and WM at 7 T (1.35 ± 0.07) was slightly less than at 3 T (1.42 ± 0.14) or 1.5 T (1.37 ± 0.07). Several major fibre bundles became visible at 7 T. One incidentally observed white matter lesion was well visible at all field strengths. Image homogeneity remains challenging and should be improved by future technical developments. FLAIR imaging at 7 T yields a high SNR,with better contrast for WM substructures and the iron-bearing basal ganglia, and has potential for good conspicuity of WM lesions.
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影响因子：
5.9
作者：
Schwindt, W;Kugel, H;Heindel, W
通讯作者：
Heindel, W
影响因子：
2.9
作者：
Barkhof, F;Scheltens, P
通讯作者：
Scheltens, P
影响因子：
1
作者：
Tkác, I;Gruetter, R
通讯作者：
Gruetter, R
影响因子：
1.3
作者：
HAJNAL, JV;DECOENE, B;BYDDER, GM
通讯作者：
BYDDER, GM
影响因子：
2.2
作者：
Garwood, M;DelaBarre, L
通讯作者：
DelaBarre, L