A neural region of abstract working memory.

A neural region of abstract working memory.
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DOI:
10.1162/jocn.2011.21625
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发表时间:
2011-10
影响因子:
3.2
通讯作者:
Christ SE
Christ SE
中科院分区:
医学3区
文献类型:
--
作者:
Cowan N;Li D;Moffitt A;Becker TM;Martin EA;Saults JS;Christ SE

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350多年前,笛卡尔提出意识的神经基础必须是将感觉输入结合在一起的大脑区域。利用功能磁共振成像技术,我们确定了至少一个这样的工作记忆区域,即记忆中的有限信息,威廉·詹姆斯将其描述为意识的后缘。具体地说,发现左侧顶内沟中的一个区域对视觉刺激(彩色方块)或视觉和听觉刺激的组合(口语字母)表现出负荷依赖性活动。这一结果在两个不同参与者和方法的实验中得到了重复。结果表明,这一以前众所周知的对视觉呈现材料的工作记忆的大脑区域,实际上持有或涉及来自不止一种通道的信息。
Over 350 years ago, Descartes proposed that the neural basis of consciousness must be a brain region in which sensory inputs are combined. Using functional magnetic resonance imaging, we identified at least one such area for working memory, the limited information held in mind, described by William James as the trailing edge of consciousness. Specifically, a region in the left intraparietal sulcus was found to demonstrate load-dependent activity for either visual stimuli (colored squares) or a combination of visual and auditory stimuli (spoken letters). This result was replicated across two experiments with different participants and methods. The results suggest that this brain region, previously well-known for working memory of visually-presented materials, actually holds or refers to information from more than one modality.
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