Genomic expansion of magnetotactic bacteria reveals an early common origin of magnetotaxis with lineage-specific evolution.
Genomic expansion of magnetotactic bacteria reveals an early common origin of magnetotaxis with lineage-specific evolution.
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趋磁细菌的基因组扩展揭示了趋磁性与谱系特异性进化的早期共同起源
DOI：
10.1038/s41396-018-0098-9
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发表时间：
2018-06
期刊：
影响因子：
--
通讯作者：
Pan Y
中科院分区：
文献类型：
--
作者：
Lin W;Zhang W;Zhao X;Roberts AP;Paterson GA;Bazylinski DA;Pan Y
在各种原核生物和原生动物中被称为趋磁的受磁能力的起源和进化，使这些微生物能够探测地球磁场以进行定向和导航，在进化生物学中尚未得到很好的理解。唯一已知的能够感知地磁场的原核生物是趋磁细菌（MTB），这是一种可移动的微生物，可将称为磁小体的磁铁矿（Fe3O4）或灰长岩（Fe3S4）的细胞内膜界磁性单畴晶体生物矿化。在结核分枝杆菌中，磁小体负责趋磁。在这里，我们报告了来自北半球和南半球的结核分枝杆菌的首次大规模宏基因组调查，并结合了来自未栽培结核分枝杆菌的28个基因组。这些基因组极大地扩大了结核分枝杆菌在变形菌门、硝化菌门和全硝化菌门中的覆盖范围，并提供了结核分枝杆菌属于Zetaproteobacteria和Candidatus Lambdaproteobacteria类的第一个基因组证据。磁小体基因簇是编码磁小体生物合成和组织蛋白质的物理分组基因，其基因含量和组织在系统发育相似的群体中比在不同的分类谱系中更为保守。此外，核心磁小体蛋白的系统发育形成单系进化枝。总之，这些结果表明，铁基（Fe3O4和Fe3S4）趋磁性在结构域细菌中有一个共同的古老起源，并经历了谱系特异性的进化，为生物矿化和趋磁性的起源和进化提供了新的思路，并显著扩大了MTB的系统基因组代表性。
The origin and evolution of magnetoreception, which in diverse prokaryotes and protozoa is known as magnetotaxis and enables these microorganisms to detect Earth’s magnetic field for orientation and navigation, is not well understood in evolutionary biology. The only known prokaryotes capable of sensing the geomagnetic field are magnetotactic bacteria (MTB), motile microorganisms that biomineralize intracellular, membrane-bounded magnetic single-domain crystals of either magnetite (Fe3O4) or greigite (Fe3S4) called magnetosomes. Magnetosomes are responsible for magnetotaxis in MTB. Here we report the first large-scale metagenomic survey of MTB from both northern and southern hemispheres combined with 28 genomes from uncultivated MTB. These genomes expand greatly the coverage of MTB in the Proteobacteria, Nitrospirae, and Omnitrophica phyla, and provide the first genomic evidence of MTB belonging to the Zetaproteobacteria and “Candidatus Lambdaproteobacteria” classes. The gene content and organization of magnetosome gene clusters, which are physically grouped genes that encode proteins for magnetosome biosynthesis and organization, are more conserved within phylogenetically similar groups than between different taxonomic lineages. Moreover, the phylogenies of core magnetosome proteins form monophyletic clades. Together, these results suggest a common ancient origin of iron-based (Fe3O4 and Fe3S4) magnetotaxis in the domain Bacteria that underwent lineage-specific evolution, shedding new light on the origin and evolution of biomineralization and magnetotaxis, and expanding significantly the phylogenomic representation of MTB.
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影响因子：
5.1
作者：
Ji, Boyang;Zhang, Sheng-Da;Wu, Long-Fei
通讯作者：
Wu, Long-Fei
影响因子：
2.7
作者：
Garrison NL;Rodriguez J;Agnarsson I;Coddington JA;Griswold CE;Hamilton CA;Hedin M;Kocot KM;Ledford JM;Bond JE
通讯作者：
Bond JE
影响因子：
11
作者：
Abreu, Fernanda;Cantao, Mauricio E.;Lins, Ulysses
通讯作者：
Lins, Ulysses
影响因子：
2.7
作者：
Kang DD;Froula J;Egan R;Wang Z
通讯作者：
Wang Z
影响因子：
5.1
作者：
Lefevre, Christopher T.;Trubitsyn, Denis;Ginet, Nicolas
通讯作者：
Ginet, Nicolas