Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
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DOI:
10.3389/fendo.2021.724632
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发表时间:
2021
影响因子:
5.2
通讯作者:
Tsukamura H
中科院分区:
文献类型:
--
作者:
Uenoyama Y;Nagae M;Tsuchida H;Inoue N;Tsukamura H
Increasing evidence accumulated during the past two decades has demonstrated that the then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin B and dynorphin A, which were discovered in 1983 and 1979, respectively, and their G-protein-coupled receptors, serve as key molecules that control reproduction in mammals. The present review provides a brief historical background and a summary of our recent understanding of the roles of hypothalamic neurons expressing kisspeptin, neurokinin B, and dynorphin A, referred to as KNDy neurons, in the central mechanism underlying gonadotropin-releasing hormone (GnRH) pulse generation and subsequent tonic gonadotropin release that controls mammalian reproduction.
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影响因子:
4.1
作者:
Castellano, J. M.;Navarro, V. M.;Tena-Sempere, M.
通讯作者:
Tena-Sempere, M.
影响因子:
56.9
作者:
BELCHETZ, PE;PLANT, TM;KNOBIL, E
通讯作者:
KNOBIL, E
DOI:
10.1073/pnas.1834399100
发表时间:
2003-09-16
影响因子:
11.1
作者:
de Roux, N;Genin, E;Milgrom, E
通讯作者:
Milgrom, E
影响因子:
4.8
作者:
DIERSCHK.DJ;BHATTACH.AN;KNOBIL, E
通讯作者:
KNOBIL, E
影响因子:
1.8
作者:
Adachi, Sachika;Yamada, Shunji;Maeda, Kei-Ichiro
通讯作者:
Maeda, Kei-Ichiro