A Live Video Dyadic Resiliency Intervention to Prevent Chronic Emotional Distress Early After Dementia Diagnoses: Protocol for a Dyadic Mixed Methods Study.
A Live Video Dyadic Resiliency Intervention to Prevent Chronic Emotional Distress Early After Dementia Diagnoses: Protocol for a Dyadic Mixed Methods Study.
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DOI：
10.2196/45532
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发表时间：
2023-09-20
影响因子：
1.7
通讯作者：
Vranceanu, Ana-Maria
中科院分区：
文献类型：
--
作者：
Bannon, Sarah;Brewer, Julie;Ahmad, Nina;Cornelius, Talea;Jackson, Jonathan;Parker, Robert A.;Dams-O'Connor, Kristen;Dickerson, Bradford C.;Ritchie, Christine;Vranceanu, Ana-Maria
到 2030 年，大约 7500 万成年人将患有阿尔茨海默病和相关痴呆症 (ADRD)。 ADRD 会导致痴呆症患者认知、情感和行为发生变化，从而损害独立性，并给痴呆症患者及其配偶护理伴侣（统称为“二人组”）带来相当大的压力源。 ADRD 诊断后，二人组成员的临床情绪困扰（即抑郁和焦虑症状）很常见，这可能会变成慢性，并对关系功能、健康、生活质量和进展症状的协作管理产生负面影响。这项研究是一项更大型研究的一部分，该研究旨在开发、调整和建立“阿尔茨海默病和相关痴呆症的弹性共同疗法”(RT-ADRD) 的可行性，这是一种基于技能的新型干预措施，旨在预防慢性情绪困扰。本研究旨在收集全面的信息来开发 RT-ADRD 的第一次迭代，并为后续的开放试点提供信息。在这里，我们描述了拟议的研究设计和程序。所有程序都将以虚拟方式进行（通过电话和 Zoom），以最大程度地减少参与者的负担，并收集有关老年人虚拟程序的可行性和最佳实践的信息。我们将在 ADRD 诊断后 1 个月内从西奈山医院 (MSH) 诊所招募双人组（最多 n=20）。两人将自行转介或由他们的治疗神经科医生转介，并完成筛查以评估情绪困扰和同意参与研究的能力。然后，双方同意后将使用采访指南参加 60 分钟的定性采访，该指南旨在评估常见挑战、未满足的需求和支持偏好，并收集有关拟议 RT-ADRD 干预内容和设计的反馈。然后，每个双人成员将有机会参加可选的个人访谈，以收集更多反馈。最后，每个双人成员将通过安全平台远程（通过手机、平板电脑或计算机）完成一项简短的定量调查，以评估评估的可行性并收集初步数据，以探索拟议的变革机制与次要结果之间的关联。我们将对可行性指标进行初步探索，包括招募、筛选、现场视频访谈、定量数据收集和混合方法分析。本研究已获得 MSH 机构审查委员会的批准。我们预计该研究将于 2023 年底完成。我们将利用这项研究的结果来开发第一个实时视频远程医疗二元弹性干预措施，重点是预防 ADRD 诊断后不久的夫妇的慢性情绪困扰。我们的研究将使我们能够从两个方面收集有关重要因素的全面信息，以在早期以预防为重点的干预中解决问题，并探索研究程序的可行性，为未来的 RT-ADRD 开放试点和试点可行性随机对照试验研究提供信息。 PRR1-10.2196/45532
By 2030, approximately 75 million adults will be living with Alzheimer disease and related dementias (ADRDs). ADRDs produce cognitive, emotional, and behavioral changes for persons living with dementia that undermine independence and produce considerable stressors for persons living with dementia and their spousal care-partners—together called a “dyad.” Clinically elevated emotional distress (ie, depression and anxiety symptoms) is common for both dyad members after ADRD diagnosis, which can become chronic and negatively impact relationship functioning, health, quality of life, and collaborative management of progressive symptoms. This study is part of a larger study that aims to develop, adapt, and establish the feasibility of Resilient Together for Alzheimer Disease and Related Dementias (RT-ADRD), a novel dyadic skills-based intervention aimed at preventing chronic emotional distress. This study aims to gather comprehensive information to develop the first iteration of RT-ADRD and inform a subsequent open pilot. Here, we describe the proposed study design and procedures. All procedures will be conducted virtually (via phone and Zoom) to minimize participant burden and gather information regarding feasibility and best practices surrounding virtual procedures for older adults. We will recruit dyads (up to n=20) from Mount Sinai Hospital (MSH) clinics within 1 month of ADRD diagnosis. Dyads will be self-referred or referred by their treating neurologists and complete screening to assess emotional distress and capacity to consent to participate in the study. Consenting dyads will then participate in a 60-minute qualitative interview using an interview guide designed to assess common challenges, unmet needs, and support preferences and to gather feedback on the proposed RT-ADRD intervention content and design. Each dyad member will then have the opportunity to participate in an optional individual interview to gather additional feedback. Finally, each dyad member will complete a brief quantitative survey remotely (by phone, tablet, or computer) via a secure platform to assess feasibility of assessment and gather preliminary data to explore associations between proposed mechanisms of change and secondary outcomes. We will conduct preliminary explorations of feasibility markers, including recruitment, screening, live video interviews, quantitative data collection, and mixed methods analyses. This study has been approved by the MSH Institutional Review Board. We anticipate that the study will be completed by late 2023. We will use results from this study to develop the first live video telehealth dyadic resiliency intervention focused on the prevention of chronic emotional distress in couples shortly after ADRD diagnoses. Our study will allow us to gather comprehensive information from dyads on important factors to address in an early prevention-focused intervention and to explore feasibility of study procedures to inform future open pilot and pilot feasibility randomized control trial investigations of RT-ADRD. PRR1-10.2196/45532
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影响因子：
6.3
作者：
Bannon, Sarah M.;Grunberg, Victoria A.;Manglani, Heena R.;Lester, Ethan G.;Ritchie, Christine;Vranceanu, Ana-Maria
通讯作者：
Vranceanu, Ana-Maria
影响因子：
3.1
作者：
Doyle, Louise;Brady, Anne-Marie;Byrne, Gobnait
通讯作者：
Byrne, Gobnait
影响因子：
2.1
作者：
Byszewski, Anna M.;Molnar, Frank J.;Bassett, Raeivyn
通讯作者：
Bassett, Raeivyn
影响因子：
4
作者：
Eldholm, Rannveig Sakshaug;Barca, Maria Lage;Saltvedt, Ingvild
通讯作者：
Saltvedt, Ingvild
影响因子：
2.7
作者：
Carver, CS
通讯作者：
Carver, CS