Saccharomyces genome database provides new regulation data.
Saccharomyces genome database provides new regulation data.
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DOI:
10.1093/nar/gkt1158
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发表时间:
2014-01
影响因子:
14.9
通讯作者:
Cherry JM
中科院分区:
文献类型:
--
作者:
Costanzo MC;Engel SR;Wong ED;Lloyd P;Karra K;Chan ET;Weng S;Paskov KM;Roe GR;Binkley G;Hitz BC;Cherry JM
The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org) is the community resource for genomic, gene and protein information about the budding yeast Saccharomyces cerevisiae, containing a variety of functional information about each yeast gene and gene product. We have recently added regulatory information to SGD and present it on a new tabbed section of the Locus Summary entitled ‘Regulation’. We are compiling transcriptional regulator–target gene relationships, which are curated from the literature at SGD or imported, with permission, from the YEASTRACT database. For nearly every S. cerevisiae gene, the Regulation page displays a table of annotations showing the regulators of that gene, and a graphical visualization of its regulatory network. For genes whose products act as transcription factors, the Regulation page also shows a table of their target genes, accompanied by a Gene Ontology enrichment analysis of the biological processes in which those genes participate. We additionally synthesize information from the literature for each transcription factor in a free-text Regulation Summary, and provide other information relevant to its regulatory function, such as DNA binding site motifs and protein domains. All of the regulation data are available for querying, analysis and download via YeastMine, the InterMine-based data warehouse system in use at SGD.
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DOI:
10.1093/bioinformatics/btr064
发表时间:
2011-04-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Grant CE;Bailey TL;Noble WS
通讯作者:
Noble WS
影响因子:
5.8
作者:
Hibbs, Matthew A.;Hess, David C.;Troyanskaya, Olga G.
通讯作者:
Troyanskaya, Olga G.
影响因子:
64.8
作者:
通讯作者:
--
影响因子:
14.9
作者:
Spivak AT;Stormo GD
通讯作者:
Stormo GD
影响因子:
2.6
作者:
Fisk, Dianna G.;Ball, Catherine A.;Cherry, J. Michael
通讯作者:
Cherry, J. Michael