The moderating role of personality factors in the relationship between depression and neuropsychological functioning among older adults.
The moderating role of personality factors in the relationship between depression and neuropsychological functioning among older adults.
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DOI：
10.1002/gps.2213
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发表时间：
2009-09
影响因子：
4
通讯作者：
Bosworth, Hayden B.
中科院分区：
文献类型：
--
作者：
Ayotte, Brian J.;Potter, Guy G.;Williams, Heather T.;Steffens, David C.;Bosworth, Hayden B.
抑郁症通常与老年人认知能力下降有关。目前的研究集中在抑郁症和非抑郁症老年人的神经心理功能和人格特质的关联。分析了75名60岁以上的抑郁症患者和103名60岁以上的非抑郁症患者的数据。所有参与者在参与之前都接受了标准化的抑郁症临床评估，并完成了NEO-PI-R和一系列神经心理学评估。本研究采用多元线性回归分析的方法，探讨了老年抑郁症患者和非抑郁症患者的人格特征与神经心理学表现之间的关系。结果表明，较高的经验开放性与抑郁老年人在连线测验A部分和B部分的较好表现有关，并且与所有参与者的较好数字广度向后表现有关。较高水平的神经质与数字跨度向后的表现较差有关，但仅在抑郁的老年人中。抑郁的参与者在符号数字模式测试和控制性口头词汇联想测试中表现更差。人格特征，特别是经验开放性，改变了老年人抑郁症和神经心理功能之间的关系。结果表明，旨在增加一个人的经验开放性的干预措施可能会削弱一些与抑郁症相关的神经心理障碍。
Depression is often associated with decreased cognitive performance among older adults. The current study focused on the association of neuropsychological functioning and personality traits in depressed and non-depressed older adults. Data from 75 depressed and 103 non-depressed adults over the age of 60 were analyzed. All participants underwent standardized clinical assessment for depression prior to participation and completed the NEO-PI-R and a series of neuropsychological assessments. A series of multiple linear regressions were conducted to examine the relationships between personality and neuropsychological performance among depressed and non-depressed older adults. Results indicated that higher Openness to Experience was related to better performance on Parts A and B of the Trail Making Test among depressed older adults, and to better Digit Span Backward performance among all participants. Higher levels of neuroticism were related to poorer performance on Digit Span Backward, but only among depressed older adults. Depressed participants performed more poorly on the Symbol Digit Modalities Test and the Controlled Oral Word Association Test. Personality characteristics, particularly Openness to Experience, modified the relationship between depression and neuropsychological functioning among older adults. Results indicate that interventions aimed at increasing one’s Openness to Experience could potentially attenuate some of the neuropsychological impairments that are associated with depression.
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