The biological functions of sphingolipids in plant pathogenic fungi.
The biological functions of sphingolipids in plant pathogenic fungi.
复制标题
DOI：
10.1371/journal.ppat.1011733
复制
发表时间：
2023-11
期刊：
影响因子：
6.7
通讯作者：
中科院分区：
文献类型：
--
作者：
Sphingolipids are critically significant in a range of biological processes in animals, plants, and fungi. In mammalian cells, they serve as vital components of the plasma membrane (PM) in maintaining its structure, tension, and fluidity. They also play a key role in a wide variety of biological processes, such as intracellular signal transduction, cell polarization, differentiation, and migration. In plants, sphingolipids are important for cell development and for cell response to environmental stresses. In pathogenic fungi, sphingolipids are crucial for the initiation and the development of infection processes afflicting humans. However, our knowledge on the metabolism and function of the sphingolipid metabolic pathway of pathogenic fungi affecting plants is still very limited. In this review, we discuss recent developments on sphingolipid pathways of plant pathogenic fungi, highlighting their uniqueness and similarity with plants and animals. In addition, we discuss recent advances in the research and development of fungal-targeted inhibitors of the sphingolipid pathway, to gain insights on how we can better control the infection process occurring in plants to prevent or/and to treat fungal infections in crops.
登录
查看更多内容
影响因子：
13.6
作者：
Fabri JHTM;de Sá NP;Malavazi I;Del Poeta M
通讯作者：
Del Poeta M
影响因子：
3.6
作者：
Cheon, Seon Ah;Bal, Jyotiranjan;Kim, Jeong-Yoon
通讯作者：
Kim, Jeong-Yoon
影响因子：
5.3
作者：
Cheng, JJ;Park, TS;Ye, XS
通讯作者：
Ye, XS
影响因子：
4.7
作者：
Elliott, Michael H.;Nash, Zack A.;Naash, Muna I.
通讯作者：
Naash, Muna I.
ORM家族蛋白介导鞘脂稳态。
影响因子：
64.8
作者：
Breslow, David K.;Collins, Sean R.;Bodenmiller, Bernd;Aebersold, Ruedi;Simons, Kai;Shevchenko, Andrej;Ejsing, Christer S.;Weissman, Jonathan S.
通讯作者：
Weissman, Jonathan S.