Neuropsychology of multiple sclerosis: a critical review.
Neuropsychology of multiple sclerosis: a critical review.
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多发性硬化症的神经心理学：批判性评论。
DOI：
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发表时间：
1986
影响因子：
2.2
通讯作者：
Stephen M. Rao
中科院分区：
文献类型：
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作者：
Stephen M. Rao
多发性硬化症(MS)是一种相对常见的慢性进行性神经系统疾病，主要影响个体在生命的第三和四十年。尸检研究表明，该病优先攻击整个中枢神经系统的白质，包括大脑半球。本文综述了关于多发性硬化症认知功能障碍的知识现状，并将这些发现与神经病理改变联系起来。情感障碍也可能由大脑脱髓鞘引起，这一观点被提出，并简要讨论了MS作为“皮质下”痴呆的原型。最后，提出了多发性硬化研究中存在的方法论问题，并对今后的研究提出了建议。
Multiple sclerosis (MS) is a relatively common, chronic progressive neurological illness affecting individuals primarily in the third and fourth decades of life. Autopsy studies indicate that the disease preferentially attacks white matter throughout the CNS, including the cerebral hemispheres. This article reviews the current state of knowledge regarding cognitive dysfunction in MS and relates these findings to neuropathological changes. The view that affective disturbance may also result from cerebral demyelination is presented, along with a brief discussion of MS as a prototype "subcortical" dementia. Finally, methodological problems intrinsic to the study of MS are presented, and suggestions for future research are made.
DOI：
10.1056/nejm198506063122303
发表时间：
1985
期刊：
The New England journal of medicine
影响因子：
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作者：
Schiffer,RB;Herndon,RM;Rudick,RA
通讯作者：
Rudick,RA