Pilot study of a culturally sensitive intervention to promote genetic counseling for breast cancer risk.
Pilot study of a culturally sensitive intervention to promote genetic counseling for breast cancer risk.
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DOI：
10.1186/s12913-022-08193-x
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发表时间：
2022-06-25
影响因子：
2.8
通讯作者：
Hoskins, Kent F.
中科院分区：
文献类型：
--
作者：
Henderson, Vida;Madrigal, Jessica M.;Kendall, Le' Chaun;Parekh, Pooja;Newsome, Jennifer;Chukwudozie, Ifeanyi Beverly;Comer-Hagans, De Lawnia;Coffey, Vickii;Grumbach, Giesela;Spencer, Shirley;Rodgers, Carolyn;Kaur, Ravneet;Balay, Lara;Maga, Tara;Ramamonjiarivelo, Zo;Balthazar, Catherine;Winn, Robert;Watson, Karriem;Odoms-Young, Angela;Hoskins, Kent F.
关键词：
尽管遗传咨询和检测有好处，但癌症遗传服务的接受率普遍较低，黑人/非裔美国人(黑人)妇女接受遗传服务的可能性比非西班牙裔白人妇女低得多。我们的团队开发了一段具有文化敏感性的叙事性决策辅助视频，以促进遗传性乳腺癌综合征高危黑人女性接受遗传咨询，该视频可以与临床环境中基于人群的癌症风险评估结合起来。我们在这里报告了一项初步研究，以证明获得遗传咨询和干预满意度的意向发生了变化。在乳房X光检查时，招募了一些黑人女性，她们本人没有受到乳腺癌的影响，并在乳房X光检查中心根据家族病史筛查被推荐接受遗传咨询。采用前瞻性的调查前研究设计，以理论结构为指导，评估基线和干预后即刻的心理社会因素，包括参与遗传咨询的意愿和干预满意度。飞行员招聘目标已实现(n= 30人)。干预前，50%的参与者表示他们极有可能预约遗传咨询，而干预后这一比例为70%(p= 0.0 5)。观看干预后，50%的参与者表示，视频改变了他们对遗传咨询的看法。这项研究展示了一项旨在激励有遗传性乳腺癌风险的黑人女性参加遗传咨询预约的决策援助干预措施的文化满足感。我们的研究表明，在旨在支持关于遗传服务的决策的干预措施中，意图可能是一个特定和关键的结构。研究结果为随后的大规模随机实施研究提供了设计依据。试验注册：Clinicaltrials.gov.NCT04082117。注册日期为2019年9月9日。追溯性注册。网上版载有补充材料，可在10.1186/s12913-022-08193-x查阅。
Despite the benefits of genetic counseling and testing, uptake of cancer genetic services is generally low and Black/African American (Black) women are substantially less likely to receive genetic services than non-Hispanic White women. Our team developed a culturally sensitive, narrative decision aid video to promote uptake of genetic counseling among Black women at risk for a hereditary breast cancer syndrome that can be incorporated in conjunction with population-based cancer risk assessment in a clinical setting. We report here a pilot study to demonstrate changes in intention to access genetic counseling and intervention satisfaction. Black women who were personally unaffected by breast cancer and were recommended for genetic counseling based on family history screening in a mammography center were recruited at the time of the mammogram. A prospective, pre-post survey study design, guided by theoretical constructs, was used to evaluate baseline and immediate post-intervention psychosocial factors, including intention to participate in genetic counseling and intervention satisfaction. Pilot recruitment goals were met (n = 30). Pre-intervention, 50% of participants indicated that they were extremely likely to make a genetic counseling appointment, compared with 70% post-intervention (p = 0.05). After watching the intervention, 50% of participants indicated that the video changed their mind regarding genetic counseling. This study demonstrated cultural satisfaction with a decision aid intervention designed to motivate Black women with hereditary breast cancer risk to attend a genetic counseling appointment. Our study showed that intention may be a specific and key construct to target in interventions designed to support decision-making about genetic services. Study results informed the design of a subsequent large scale, randomized implementation study. Trial registration: Clinicaltrials.govNCT04082117. Registered September 9, 2019. Retrospectively registered. The online version contains supplementary material available at 10.1186/s12913-022-08193-x.
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