Supplementation with a Flavanol‐rich Lychee Fruit Extract Influences the Inflammatory Status of Young Athletes
Supplementation with a Flavanol‐rich Lychee Fruit Extract Influences the Inflammatory Status of Young Athletes
复制标题
补充富含黄烷醇的荔枝果实提取物会影响年轻运动员的炎症状态
作者：
M. Nishizawa;Takafumi Hara;T. Miura;S. Fujita;E. Yoshigai;H. Ue;Y. Hayashi;A. Kwon;T. Okumura;T. Isaka
富含黄烷醇的荔枝果实提取物（FRLFE）是一种加工的荔枝果实提取物，其黄烷醇（单体、二聚体和三聚体）含量高于其未加工的对应物。FRLFE在体外发挥抗氧化活性，并有望防止炎症和组织损伤。然而，尚未在体内探索FRLFE摄入的生理效应。本研究的目的是检查在激烈的体育训练期间，FRLFE补充剂对年轻运动员炎症和组织损伤的影响。在一所大学里，20名健康的男性长跑运动员以双盲方式被随机分配接受FRLFE或安慰剂。在2个月的训练期之前（训练前）、期间（训练中）和之后（训练后），评估与炎症、组织损伤和氧化应激相关的血液和血清参数。一些参数，包括白色血细胞计数，通过FRLFE补充显著改变。与安慰剂组相比，FRLFE组训练前后血清白细胞介素-6水平的变化显著较低，而FRLFE组训练前后转化生长因子-β水平的变化显著较高。这些发现表明，FRLFE补充剂可以抑制高强度运动训练引起的炎症或组织损伤。版权所有© 2011约翰威利父子有限公司.
Flavanol‐rich lychee fruit extract (FRLFE) is a processed lychee fruit extract that is higher in flavanols (monomers, dimers and trimers) than its unprocessed counterpart. FRLFE exerts antioxidant activities in vitro and is expected to protect against inflammation and tissue damage. However, the physiological effects of FRLFE intake have not been explored in vivo. The aim of this study was to examine the effects of FRLFE supplementation on inflammation and tissue damage in young athletes during intense physical training. Twenty healthy male long‐distance runners at a university were randomly assigned to receive FRLFE or placebo in a double‐blind manner. Blood and serum parameters associated with inflammation, tissue damage and oxidative stress were evaluated before (pre‐training), during (mid‐training) and after (post‐training) a 2‐month training period. Some parameters, including the white blood cell count, were significantly modified by FRLFE supplementation. Compared with the placebo group, the change in the serum interleukin‐6 level between pre‐ and mid‐training were significantly lower in the FRLFE group, while the change in the transforming growth factor‐β level between pre‐ and post‐training was significantly greater in the FRLFE group. These findings suggest that FRLFE supplementation may suppress inflammation or tissue damage caused by high‐intensity exercise training. Copyright © 2011 John Wiley & Sons, Ltd.
影响因子：
2.9
作者：
GREEN, LC;WAGNER, DA;TANNENBAUM, SR
通讯作者：
TANNENBAUM, SR