The deep roots of the rings of life.
The deep roots of the rings of life.
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DOI：
10.1093/gbe/evt194
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发表时间：
2013
影响因子：
3.3
通讯作者：
Sinsheimer JS
中科院分区：
文献类型：
--
作者：
Lake JA;Sinsheimer JS
Reconstructing early evolutionary events like the origins of informational and operational genes, membranes, and photophosphorylation is difficult because early evolutionary events can be masked by subsequent gene flows. Furthermore, as evolution progresses through both Darwinian survival of the fittest (tree-like evolution) and symbiotic/endosymbiotic cooperation (ring-like evolution), trees alone are not adequate to represent Earth’s evolutionary history. Here, we reconstruct and root the New Rings of Life and use it as a framework for interpreting early events in the evolution of life. Unlike the three-domain hypothesis, the rings do not fit all life into one of three immutable categories, but rather accommodate new gene flows as novel organisms are discovered. A draft of the Rooted Rings of Life is reconstructed by analyzing the phylogenetic distributions of indels (insertions/deletions) and genes coding for fundamental molecular processes. Their phylogenetic distributions are inconsistent with all trees. Hypergeometric distribution analyses of them strongly localize the root of the rings to a segment of the deepest ring (P < 10−21 and P < 10−194), and whole-genome analyses independently confirm the topology of the rooted rings (P < 7.1 × 10−6). The rings identify several large gene flows, including a flow of a thousand genes into the Halobacteria and the Eubacteria, the related photocyte flow, the flow of genes into the last common ancestor of the eocytes and the eukaryotes, and the informational and operational gene flows into the eukaryotes. The rooted rings also chronologically order steps in the evolution of extant taxa, that is, phototrophy evolved from Halobacteria (photophosphorylation) → Heliobacteria (photosynthesis) → Cyanobacteria (oxygenic photosynthesis).
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影响因子：
11.3
作者：
Higgins D;Dworkin J
通讯作者：
Dworkin J
DOI：
10.1073/pnas.81.12.3786
发表时间：
1984-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
LAKE, JA;HENDERSON, E;CLARK, MW
通讯作者：
CLARK, MW
影响因子：
64.8
作者：
Rivera, MC;Lake, JA
通讯作者：
Lake, JA
影响因子：
64.8
作者：
Bekker, A;Holland, HD;Beukes, NJ
通讯作者：
Beukes, NJ
DOI：
10.1073/pnas.0810647105
发表时间：
2008-12-23
影响因子：
11.1
作者：
Cox, Cymon J.;Foster, Peter G.;Embley, T. Martin
通讯作者：
Embley, T. Martin