Darcy Permeability of Hollow Fiber Bundles Used in Blood Oxygenation Devices.
Darcy Permeability of Hollow Fiber Bundles Used in Blood Oxygenation Devices.
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DOI：
10.1016/j.memsci.2011.08.012
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发表时间：
2011-10-15
影响因子：
9.5
通讯作者：
Federspiel, William J.
中科院分区：
文献类型：
--
作者：
Pacella, Heather E.;Eash, Heidi J.;Frankowski, Brian J.;Federspiel, William J.
关键词：
许多工业和生物医学设备（例如血液氧合器和人工肺）使用中空纤维膜束进行分离过程。纤维束壳侧内的流动和质量传输的分析最经常为简单起见将纤维束建模为填充床或多孔介质，使用从Blake-Kozeny方程估计的达西渗透系数来解释来自纤维的粘性阻力。在这项研究中，我们开发了一种简单的方法来测量达西渗透中空纤维膜束和评估如何以及布莱克-Kozeny（BK）方程预测达西渗透这些束。纤维束由市售的Celgard® X 30-240纤维织物（300 μm外径纤维@35和54纤维/英寸）和具有193 μm纤维（61纤维/英寸）的纤维织物制成。将纤维束安装到丙烯酸管的底部，并通过测量甘油溶液柱流过纤维束的经过时间来确定达西渗透率。实测达西渗透率与BK方程预测渗透率之比为1.09 ~ 0.56。综合文献回顾，提出了一个修正的BK方程与孔隙度相关的“常数”。这种修改改进了BK方程的预测，测量渗透率与预测渗透率的比值从1.13变化到0.84。
Many industrial and biomedical devices (e.g. blood oxygenators and artificial lungs) use bundles of hollow fiber membranes for separation processes. Analyses of flow and mass transport within the shell-side of the fiber bundles most often model the bundle for simplicity as a packed bed or porous media, using a Darcy permeability coefficient estimated from the Blake-Kozeny equation to account for viscous drag from the fibers. In this study, we developed a simple method for measuring the Darcy permeability of hollow fiber membrane bundles and evaluated how well the Blake-Kozeny (BK) equation predicted the Darcy permeability for these bundles. Fiber bundles were fabricated from commercially available Celgard® ×30-240 fiber fabric (300 μm outer diameter fibers @ 35 and 54 fibers/inch) and from a fiber fabric with 193 μm fibers (61 fibers/inch). The fiber bundles were mounted to the bottom of an acrylic tube and Darcy permeability was determined by measuring the elapsed time for a column of glycerol solution to flow through a fiber bundle. The ratio of the measured Darcy permeability to that predicted from the BK equation varied from 1.09 to 0.56. A comprehensive literature review suggested a modified BK equation with the “constant” correlated to porosity. This modification improved the predictions of the BK equation, with the ratio of measured to predicted permeability varying from 1.13 to 0.84.
影响因子：
3.7
作者：
Zhang, GL;Cussler, EL
通讯作者：
Cussler, EL
影响因子：
2.4
作者：
Gartner, MJ;Wilhelm, CR;Wagner, WR
通讯作者：
Wagner, WR
影响因子：
2.4
作者：
VASLEF, SN;MOCKROS, LF;ANDERSON, RW
通讯作者：
ANDERSON, RW