Advances in the techniques for the prediction of microRNA targets.
Advances in the techniques for the prediction of microRNA targets.
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microRNA靶标预测技术的进展
DOI:
10.3390/ijms14048179
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发表时间:
2013-04-15
影响因子:
5.6
通讯作者:
Jiang SW
中科院分区:
文献类型:
--
作者:
Zheng H;Fu R;Wang JT;Liu Q;Chen H;Jiang SW
MicroRNAs (miRNAs) are small, non-coding, endogenous RNA molecules that play important roles in a variety of normal and diseased biological processes by post-transcriptionally regulating the expression of target genes. They can bind to target messenger RNA (mRNA) transcripts of protein-coding genes and negatively control their translation or cause mRNA degradation. miRNAs have been found to actively regulate a variety of cellular processes, including cell proliferation, death, and metabolism. Therefore, their study is crucial for the better understanding of cellular functions in eukaryotes. To better understand the mechanisms of miRNA: mRNA interaction and their cellular functions, it is important to identify the miRNA targets accurately. In this paper, we provide a brief review for the advances in the animal miRNA target prediction methods and available resources to facilitate further study of miRNAs and their functions.
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影响因子:
3
作者:
Hsu JB;Chiu CM;Hsu SD;Huang WY;Chien CH;Lee TY;Huang HD
通讯作者:
Huang HD
影响因子:
14.9
作者:
Anders G;Mackowiak SD;Jens M;Maaskola J;Kuntzagk A;Rajewsky N;Landthaler M;Dieterich C
通讯作者:
Dieterich C
影响因子:
14.9
作者:
Khorshid M;Rodak C;Zavolan M
通讯作者:
Zavolan M
影响因子:
3.7
作者:
Engelmann JC;Spang R
通讯作者:
Spang R
影响因子:
16.8
作者:
Long, Dang;Lee, Rosalind;Ding, Ye
通讯作者:
Ding, Ye