The Effect of Robot-Assisted Gait Training on Locomotor Function and Functional Capability for Daily Activities in Children with Cerebral Palsy: A Single-Blinded, Randomized Cross-Over Trial.

The Effect of Robot-Assisted Gait Training on Locomotor Function and Functional Capability for Daily Activities in Children with Cerebral Palsy: A Single-Blinded, Randomized Cross-Over Trial.
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机器人辅助步态训练对脑瘫儿童运动功能和日常活动功能的影响:一项单盲、随机交叉试验。

DOI:
10.3390/brainsci10110801
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发表时间:
2020-10-30
期刊:
影响因子:
3.3
通讯作者:
Sohn MK
Sohn MK
中科院分区:
医学4区
文献类型:
--
作者:
Jin LH;Yang SS;Choi JY;Sohn MK

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目的:机器人辅助步态训练(RAGT)在脑瘫(CP)儿童中的有效性,特别是在改善日常活动表现方面,仍不清楚。因此,我们的目的是探讨RAGT在儿童CP中的有效性。研究方法:在这项单中心、单盲、随机交叉试验中,我们入组了20名粗大运动功能分类系统(GMFCS)II-IV级的CP儿童(13名男性;年龄范围,6.75 ± 2.15岁)。受试者随机分为RAGT/标准治疗(SC)组(n = 10)和SC/RAGT/SC序列组(n = 10)。使用Walkbot-K系统,RAGT计划包括每周3次30分钟的训练,持续6周,并继续SC计划。SC计划包括每周2-4次常规物理治疗,持续6周。在RAGT或SC期间前后评估粗大运动功能测量-88(GMFM-88)、儿科功能独立性测量(Weeweigh)和加拿大职业表现测量(COPM)评分,并分析治疗、期间、随访和遗留效应。能量消耗和身体成分进行了测量前和后RAGT。结果如下:在GMFM的D和E维度(D:p = 0.018; E:p = 0.021)评分、Weeker移动性小计(p = 0.007)、COPM性能(p < 0.001)和满意度(p = 0.001)测量评分中观察到显著的治疗效果。期间、随访和遗留效应无统计学显著性。RAGT后评估时,总能量成本显著降低(p = 0.041),骨骼肌质量增加(p = 0.014)。与功能结局相关的因素显示GMFM D评分显著改善,与IV级儿童相比,主要在GMFCS II-III级儿童中观察到(p = 0.038)。结论:RAGT对脑瘫患儿有一定的训练效果。具体而言,它改善了运动功能和日常活动的功能能力。这些效果在患有CP的非卧床儿童中更好。然而,由于在RAGT期间继续进行SC干预,这些改善也可能与多种治疗效应相关。
Purpose: The effectiveness of robot-assisted gait training (RAGT) in children with cerebral palsy (CP), especially in terms of improving the performance of daily activities, remains unclear. Therefore, we aimed to investigate the effectiveness of RAGT in children with CP. Methods: In this single-center, single-blinded, randomized cross-over trial, we enrolled 20 children with CP with Gross Motor Function Classification System (GMFCS) levels II–IV (13 males; age range, 6.75 ± 2.15 years). The participants were randomized into the RAGT/standard care (SC) (n = 10) and SC/RAGT/SC sequence groups (n = 10). Using a Walkbot-K system, the RAGT program comprised 3 × 30-min sessions/week for 6 weeks with a continued SC program. The SC program comprised 2–4 conventional physiotherapy sessions/week for 6 weeks. The Gross Motor Function Measure-88 (GMFM-88), the pediatric functional independence measure (WeeFIM), and the Canadian occupational performance measure (COPM) scores were assessed pre- and post-RAGT or SC periods and treatment, period, follow-up, and carry-over effects were analyzed. Energy expenditure and body composition were measured pre- and post-RAGT. Results: Significant treatment effects were observed in dimensions D and E of the GMFM (D: p = 0.018; E: p = 0.021) scores, WeeFIM mobility subtotal (p = 0.007), and COPM performance (p < 0.001) and satisfaction (p = 0.001) measure scores. The period, follow-up, and carry-over effects were not statistically significant. The gross energy cost significantly decreased (p = 0.041) and the skeletal muscle mass increased (p = 0.014) at post-RAGT assessment. The factors associated with functional outcomes showed significant improvements in the GMFM D scores and were mainly observed in children with GMFCS levels II–III compared to those classified at level IV (p = 0.038). Conclusion: RAGT had training benefits for children with CP. Specifically, it improved locomotor function and functional capability for daily activities. These effects were better in ambulatory children with CP. However, as SC interventions continued during the RAGT period, these improvements may be also related to multiple treatment effects.
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