Future Prospects of Spectral Clustering Approaches in Proteomics.

Future Prospects of Spectral Clustering Approaches in Proteomics.
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DOI:
10.1002/pmic.201700454
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发表时间:
2018-07
期刊:
影响因子:
3.4
通讯作者:
Griss J
Griss J
中科院分区:
生物学3区
文献类型:
--
作者:
Perez-Riverol Y;Vizcaíno JA;Griss J

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In this article, current and future applications of spectral clustering are discussed in the context of mass spectrometry‐based proteomics approaches. First of all, the main algorithms and tools that can currently be used to perform spectral clustering are introduced. In addition, its main applications and their use in current computational proteomics workflows are explained, including the generation of spectral libraries and spectral archives. Finally, possible future directions for spectral clustering, including its potential use to achieve a deeper coverage of the proteome and the discovery of novel post‐translational modifications and single amino acid variants.
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