Changes in ribo- and deoxyribonucleoside triphosphate pools within the cell cycle of a synchronized mouse fibroblast cell line.
Changes in ribo- and deoxyribonucleoside triphosphate pools within the cell cycle of a synchronized mouse fibroblast cell line.
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同步小鼠成纤维细胞系细胞周期内核糖核苷和脱氧核糖核苷三磷酸库的变化。
DOI：
10.1016/0304-4165(83)90021-1
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Bertram,JS
中科院分区：
文献类型：
--
作者：
McCormick,PJ;Danhauser,LL;Rustum,YM;Bertram,JS
Intracellular pool levels of ribo- and deoxyribonucleoside triphosphates were monitored throughout the cell cycle of C3H10T1/2 mouse embryo fibrolast cells synchronized by isoleucine deprivation. Absolute pool sizes of ribonucleoside triphosphates were approximately 30 fold greater than those of the corresponding deoxyribonucleoside triphosphates. Of the ribonucleoside triphosphates, pool sizes of ATP exhibited the greatest change, increasing from a low of 32.7 nmol/107cells during G1to a high of 81.6 nmol/107cells 2 h prior to mid S-phase. Levels of ATP subsequently declined to 40.2 nmol/107cells during late S-phase, followed by a second peak of 65.8 nmol/107with the onset of cell division. No significant changes in the pool sizes of UTP and GTP were found throughout the cell cycle. Of the deoxyribonucleoside triphosphates, pool sizes of pyrimidine deoxyribonucleoside triphosphates were approx. 5–10 fold greater than those of purine deoxyribonucleoside triphosphates. Low levels of deoxyribonucleoside triphosphates during G1(0.3–1.3 pmol/107cells) increased coordinately with the initiation of DNA synthesis to an initial peak during mid S-phase (0.5–6.4 pmol/107cells). Decling levels of deoxyribonucleoside triphosphates during late S-phase were followed by a subsequent larger second peak (1.7–10.7 pmol/107cells) during G2-M.
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影响因子：
7.8
作者：
Hartwell, L H
通讯作者：
Hartwell, L H
真核细胞细胞周期的调节。
DOI：
10.1016/s0074-7696(08)62324-4
发表时间：
1981
期刊：
International review of cytology
影响因子：
--
作者：
R. Yanishevsky;Gretchen H. Stein
通讯作者：
Gretchen H. Stein
梨形四膜虫同步群体中的核糖核苷酸和脱氧核糖核苷酸三磷酸池。
DOI：
10.1016/0005-2787(75)90131-8
发表时间：
1975
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
B. Nexø
通讯作者：
B. Nexø
DOI：
10.1016/0005-2787(72)90425-x
发表时间：
1972-01-01
期刊：
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子：
--
作者：
BRAY, G;BRENT, TP
通讯作者：
BRENT, TP
羟基脲和 1-β-D-阿拉伯呋喃糖基-胞嘧啶对小鼠胚胎细胞脱氧核糖核苷酸池的影响。
DOI：
--
发表时间：
1971
期刊：
European Journal of Biochemistry
影响因子：
--
作者：
Lambert Skoog;B. Nordenskjöld
通讯作者：
B. Nordenskjöld