A performance-optimizing compiler for cyber-physical digital microfluidic biochips
A performance-optimizing compiler for cyber-physical digital microfluidic biochips
复制标题
用于网络物理数字微流控生物芯片的性能优化编译器
DOI:
10.1145/3368826.3377925
复制
发表时间:
2020
期刊:
影响因子:
--
通讯作者:
Brisk, Philip
中科院分区:
文献类型:
--
作者:
Loveless, Tyson;Ott, Jason;Brisk, Philip
This paper introduces a compiler optimization strategy for Software-Programmable Laboratories-on-a-Chip (SP-LoCs), which miniaturize and automate a wide variety of benchtop laboratory experiments. The compiler targets a specific class of SP-LoCs that manipulate discrete liquid droplets on a 2D grid, with cyber-physical feedback provided by integrated sensors and/or video monitoring equipment. The optimization strategy employed here aims to reduce the overhead of transporting fluids between operations, and explores tradeoffs between the latency and resource requirements of mixing operations: allocating more space for mixing shortens mixing time, but reduces the amount of spatial parallelism available to other operations. The compiler is empirically evaluated using a cycle-accurate simulator that mimics the behavior of the target SP-LoC. Our results show that a coalescing strategy, inspired by graph coloring register allocation, effectively reduces droplet transport latencies while speeding up the compiler and reducing its memory footprint. For biochemical reactions that are dominated by mixing operations, we observe a linear correlation between a preliminary result using a default mixing operation resource allocation and the percentage decrease in execution time that is achieved via resizing.
登录
查看更多内容
DOI:
--
发表时间:
2006
期刊:
Proceedings of the Design Automation & Test in Europe Conference
影响因子:
--
作者:
A. Ricketts;K. M. Irick;N. Vijaykrishnan;M. J. Irwin
通讯作者:
M. J. Irwin
DOI:
--
发表时间:
2014
期刊:
2014 IEEE Dallas Circuits and Systems Conference (DCAS)
影响因子:
--
作者:
Yiyan Li;Hongzhong Li;R. J. Baker
通讯作者:
R. J. Baker
DOI:
--
发表时间:
2016
影响因子:
2.9
作者:
Mirela Alistar;P. Pop;J. Madsen
通讯作者:
J. Madsen
DOI:
10.1145/3168826
发表时间:
2018
期刊:
Proceedings of the 2018 International Symposium on Code Generation and Optimization - CGO 2018
影响因子:
--
作者:
Curtis, Christopher;Grissom, Daniel;Brisk, Philip
通讯作者:
Brisk, Philip
DOI:
10.1109/tcad.2016.2600626
发表时间:
2017-05-01
影响因子:
2.9
作者:
Ibrahim, Mohamed;Chakrabarty, Krishnendu;Scott, Kristin
通讯作者:
Scott, Kristin