Understanding the Impact of Hazardous and Harmful Use of Alcohol and/or Other Drugs on ARV Adherence and Disease Progression.
Understanding the Impact of Hazardous and Harmful Use of Alcohol and/or Other Drugs on ARV Adherence and Disease Progression.
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DOI:
10.1371/journal.pone.0125088
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发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Parry C
中科院分区:
文献类型:
--
作者:
Kader R;Govender R;Seedat S;Koch JR;Parry C
The objective of this study was to understand the impact of hazardous and harmful use of alcohol and/or other drugs on ARV adherence and disease progression among HIV patients. A cross-sectional study design was used. A total of 1503 patients attending HIV clinics in Cape Town, South Africa were screened for problematic substance use. A sub-sample of 607 patients (303 patients who screened positive for problematic substance use and 304 who did not) participated in this study. Hazardous or harmful alcohol use and problematic drug use predicted missing and stopping ARVs which, in turn, was associated with a decrease in CD4 counts and more rapid HIV-disease progression and poorer health outcomes in people living with HIV/AIDS (PLWHA). The findings of this study underscore the need for an integrated approach to managing substance-use disorders in PLWHA.
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DOI:
10.1177/1545109710371133
发表时间:
2010-07-01
期刊:
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)
影响因子:
--
作者:
Farley, John;Miller, Erin;Blattner, William
通讯作者:
Blattner, William
DOI:
10.1097/00126334-200107010-00006
发表时间:
2001-07-01
期刊:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
影响因子:
--
作者:
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通讯作者:
Moore, RD
影响因子:
4.9
作者:
Mellins, CA;Kang, E;Chesney, MA
通讯作者:
Chesney, MA
影响因子:
3.7
作者:
Palepu, A.;Khan, N. A.;Dodek, P. M.
通讯作者:
Dodek, P. M.
影响因子:
5.7
作者:
Cook, RL;Sereika, SM;Conigliaro, J
通讯作者:
Conigliaro, J