Lipotoxic Proximal Tubular Injury: A Primary Event in Diabetic Kidney Disease.
Lipotoxic Proximal Tubular Injury: A Primary Event in Diabetic Kidney Disease.
复制标题
脂毒性近端肾小管损伤:糖尿病肾病的主要事件
DOI:
10.3389/fmed.2021.751529
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发表时间:
2021
影响因子:
3.9
通讯作者:
Guo J
中科院分区:
文献类型:
--
作者:
Wang H;Zhang S;Guo J
The pathogenesis of diabetic nephropathy is a complex process that has a great relationship with lipotoxicity. Since the concept of “nephrotoxicity” was proposed, many studies have confirmed that lipotoxicity plays a significant role in the progression of diabetic nephropathy and causes various renal dysfunction. This review will make a brief summary of renal injury caused by lipotoxicity that occurs primarily and predominantly in renal tubules during diabetic progression, further leading to glomerular dysfunction. The latest research suggests that lipotoxicity-mediated tubular injury may be a major event in diabetic nephropathy.
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DOI:
10.1016/j.jnutbio.2010.01.005
发表时间:
2010-11
期刊:
The Journal of nutritional biochemistry
影响因子:
--
作者:
Atshaves BP;Martin GG;Hostetler HA;McIntosh AL;Kier AB;Schroeder F
通讯作者:
Schroeder F
影响因子:
5.1
作者:
Cho, N. H.;Shaw, J. E.;Malanda, B.
通讯作者:
Malanda, B.
影响因子:
3.7
作者:
Hong YA;Lim JH;Kim MY;Kim TW;Kim Y;Yang KS;Park HS;Choi SR;Chung S;Kim HW;Kim HW;Choi BS;Chang YS;Park CW
通讯作者:
Park CW
影响因子:
19.6
作者:
通讯作者:
--
影响因子:
3.6
作者:
Fu, Yanqin;Wang, Chongxian;Chu, Xiaojing
通讯作者:
Chu, Xiaojing