Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial.
Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial.
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DOI：
10.1007/s00125-008-0950-y
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发表时间：
2008-05
期刊：
影响因子：
8.2
通讯作者：
van Loon, L. J. C.
中科院分区：
文献类型：
--
作者：
Praet, S. F. E.;van Rooij, E. S. J.;Wijtvliet, A.;Boonman-de Winter, L. J. M.;Enneking, Th.;Kuipers, H.;Stehouwer, C. D. A.;van Loon, L. J. C.
关键词：
结构化运动被认为是 2 型糖尿病治疗的基石。然而，抵抗和耐力联合运动或医疗健身干预计划的坚持程度普遍较差。以团体为基础的快走可能是一种有吸引力的选择，但与医疗健身干预计划等个性化方法相比，其长期疗效尚不清楚。我们比较了 2 型糖尿病患者为期 12 个月的运动干预计划（包括快走或医疗健身计划）的临床益处。我们将 92 名 2 型糖尿病患者（60±9 岁）随机分为每周 3 次 60 分钟快走 (n = 49) 或医疗健身计划 (n = 43)。主要结果是 12 个月时 HbA1c 值变化的差异。次要结果是血压、血脂浓度、胰岛素敏感性、身体成分、体能、计划依从率和健康相关生活质量变化的差异。 12 个月后，18 名快走和 19 名医疗健身参与者仍然积极参与。在这两个项目中，50% 和 25% 的退出者分别是由于过度使用伤害和缺乏动力而导致的。意向治疗分析显示快走和医疗健身计划在主要或次要结果变量方面没有显着差异。与更个性化的医疗健身计划相比，基于团体的快走处方是调节 2 型糖尿病患者血糖控制和心血管风险状况的同等有效的干预措施。未来的运动干预计划应该预见到由于过度使用伤害和动机问题而导致的高流失率。本文的在线版本 (doi:10.1007/s00125-008-0950-y) 包含补充材料，可供授权用户使用。
Structured exercise is considered a cornerstone in type 2 diabetes treatment. However, adherence to combined resistance and endurance type exercise or medical fitness intervention programmes is generally poor. Group-based brisk walking may represent an attractive alternative, but its long-term efficacy as compared with an individualised approach such as medical fitness intervention programmes is unknown. We compared the clinical benefits of a 12-month exercise intervention programme consisting of either brisk walking or a medical fitness programme in type 2 diabetes patients. We randomised 92 type 2 diabetes patients (60 ± 9 years old) to either three times a week of 60 min brisk walking (n = 49) or medical fitness programme (n = 43). Primary outcome was the difference in changes in HbA1c values at 12 months. Secondary outcomes were differences in changes in blood pressure, plasma lipid concentrations, insulin sensitivity, body composition, physical fitness, programme adherence rate and health-related quality of life. After 12 months, 18 brisk walking and 19 medical fitness participants were still actively participating. In both programmes, 50 and 25% of the dropout was attributed to overuse injuries and lack of motivation, respectively. Intention-to-treat analyses showed no important differences between brisk walking and medical fitness programme in primary or secondary outcome variables. The prescription of group-based brisk walking represents an equally effective intervention to modulate glycaemic control and cardiovascular risk profile in type 2 diabetes patients when compared with more individualised medical fitness programmes. Future exercise intervention programmes should anticipate the high attrition rate due to overuse injuries and motivation problems. The online version of this article (doi:10.1007/s00125-008-0950-y) contains supplementary material, which is available to authorised users.
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