Parkinson's disease and age-related alterations in brain oscillations during a Simon task
Parkinson's disease and age-related alterations in brain oscillations during a Simon task
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西蒙任务期间帕金森病和与年龄相关的大脑振荡变化
DOI：
10.1097/wnr.0b013e32801421e3
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发表时间：
2007
期刊：
影响因子：
1.7
通讯作者：
C. Başar
中科院分区：
文献类型：
--
作者：
C. Schmiedt;G. Schwendemann;M. Herrmann;C. Başar
本研究调查了11名帕金森病患者，11名年龄匹配的患者和11名年轻参与者与西蒙任务相关的事件相关振荡。在这个任务中，当刺激和反应的相对空间位置匹配时（不存在反应冲突），参与者的反应速度比当它们不匹配时（存在反应冲突）更快。与年轻参与者相比，老年对照组和帕金森病患者的反应冲突增加（反应时间增加，称为西蒙效应）。δ和频率范围存在群体和条件差异，这可能反映了帕金森病患者和匹配对照组使用不同的认知策略进行刺激-反应处理，并且与年龄匹配对照组相比，患者缺乏这种策略的神经生理相关性。
This study investigated event-related oscillations associated with a Simon task in 11 Parkinson's disease patients, 11 age-matched, and 11 young participants. During this task, participants respond faster when the relative spatial positions of stimulus and response match (no response conflict exists) than when they do not match (response conflict exists). An increased response conflict (increase in reaction times known as Simon effect) was found in elderly control and Parkinson's patients compared with young participants. Group and condition differences were found in the δ and &thetas; frequency range, which may reflect that Parkinson's patients and matched controls use different cognitive strategies for stimulus–response processing than young controls and neurophysiological correlates of such strategy are deficient in patients compared with age-matched controls.
DOI：
10.1016/s0168-5597(97)96139-6
发表时间：
1997-05-01
期刊：
EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
Polich, J
通讯作者：
Polich, J