The ARRIVE guidelines 2.0: updated guidelines for reporting animal research.
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research.
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DOI：
10.1136/bmjos-2020-100115
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发表时间：
2020-07-20
期刊：
影响因子：
--
通讯作者：
Würbel H
中科院分区：
文献类型：
--
作者：
Percie du Sert N;Hurst V;Ahluwalia A;Alam S;Avey MT;Baker M;Browne WJ;Clark A;Cuthill IC;Dirnagl U;Emerson M;Garner P;Holgate ST;Howells DW;Karp NA;Lazic SE;Lidster K;MacCallum CJ;Macleod M;Pearl EJ;Petersen OH;Rawle F;Reynolds P;Rooney K;Sena ES;Silberberg SD;Steckler T;Würbel H
可再生科学需要透明的报告。ARRIVE指南（动物研究：体内实验报告）最初于2010年制定，旨在改进动物研究报告。它们包括一份信息清单，将包括在描述体内实验的出版物中，以使其他人能够充分审查工作，评估其方法的严谨性并复制方法和结果。尽管多年来得到了资助者和期刊的相当程度的认可，但对指导方针的遵守一直不一致，动物研究出版物报告质量的预期改进尚未实现。在这里，我们介绍ARRIVE 2.0。指引已更新，资料亦已重组，以方便在实务中使用。我们使用德尔菲练习来确定优先级并将指南项目分为两组，“到达基本10”，构成最低要求，“推荐集”，描述研究背景。该司通过支持逐步实施的方法，促进改进动物研究报告。这有助于期刊编辑和审稿人验证手稿中报告的最重要的项目。我们还制定了附带的解释和细化文件，用于(1)解释指导方针中每个项目背后的基本原理，(2)澄清关键概念，以及(3)提供说明性示例。我们的目标是，通过这些变化，帮助确保研究人员、审稿人和期刊编辑能够更好地提高科学过程的严谨性和透明度，从而提高可重复性。
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour and reproduce the methods and results. Despite considerable levels of endorsement by funders and journals over the years, adherence to the guidelines has been inconsistent, and the anticipated improvements in the quality of reporting in animal research publications have not been achieved. Here, we introduce ARRIVE 2.0. The guidelines have been updated and information reorganised to facilitate their use in practice. We used a Delphi exercise to prioritise and divide the items of the guidelines into two sets, the ‘ARRIVE Essential 10’, which constitutes the minimum requirement, and the ‘Recommended Set’, which describes the research context. This division facilitates improved reporting of animal research by supporting a stepwise approach to implementation. This helps journal editors and reviewers verify that the most important items are being reported in manuscripts. We have also developed the accompanying Explanation and Elaboration document, which serves (1) to explain the rationale behind each item in the guidelines, (2) to clarify key concepts and (3) to provide illustrative examples. We aim, through these changes, to help ensure that researchers, reviewers and journal editors are better equipped to improve the rigour and transparency of the scientific process and thus reproducibility.
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影响因子：
17.1
作者：
Goodman, Steven N.;Fanelli, Daniele;Ioannidis, John P. A.
通讯作者：
Ioannidis, John P. A.
影响因子：
9.8
作者：
Percie du Sert N;Bamsey I;Bate ST;Berdoy M;Clark RA;Cuthill I;Fry D;Karp NA;Macleod M;Moon L;Stanford SC;Lings B
通讯作者：
Lings B
影响因子：
--
作者：
Freedman LP;Venugopalan G;Wisman R
通讯作者：
Wisman R
影响因子：
3.7
作者：
Ancker, Jessica S.;Flanagin, Annette
通讯作者：
Flanagin, Annette
影响因子：
3.7
作者：
Kilkenny C;Parsons N;Kadyszewski E;Festing MF;Cuthill IC;Fry D;Hutton J;Altman DG
通讯作者：
Altman DG