Ultrastructural identification of different subtypes of interstitial cells of Cajal in the chicken ileum.
Ultrastructural identification of different subtypes of interstitial cells of Cajal in the chicken ileum.
复制标题
鸡回肠中卡哈尔间质细胞不同亚型的超微结构鉴定。
DOI：
10.3382/ps.2011-02090
复制
发表时间：
2012
期刊：
影响因子：
4.4
通讯作者：
Qiusheng Chen
中科院分区：
文献类型：
--
作者：
P. Yang;Song Wang;J. A. Gandahi;J. A. Gandahi;X. Bian;L. Wu;Yingsen Liu;L. Zhang;Q. Zhang;Qiusheng Chen
不同亚型的Cajal间质细胞(ICC)在鸟类中的超微结构特征尚不清楚，但鸟类具有显著的经济和科学意义。我们的目的是描述和分类鸡内脏中的ICC。对3只正常成年黄羽肉鸡(n=10)的回肠进行了透射电子显微镜观察。ICC呈梭形或星形，细胞突起分叉。它们有大量的线粒体，丰富的中间fi片段，梭形核(椭圆形或锯齿状)，外周异染色质致密带，彼此之间以及与邻近的平滑肌细胞之间通过真正的缝隙连接形成紧密的接触。ICC与肠神经密切接触，但未见真正的缝隙连接。在粘膜固有层发现了一种新的ICC亚型。部分ICC具有典型的SMC特征，包括基底板、小凹和致密小体。由于缺乏中间丝和小凹，它们有别于成纤维细胞样细胞，显示出发达的分泌细胞器，包括包被的小泡和片状的基底膜。鸡肠道ICC的超微结构特征和分布与哺乳动物相似。它们可能在胃肠运动中起着类似的关键调节作用。在粘膜固有层中发现的ICC新亚型可能在分泌和吸收调节中发挥作用。
Ultrastructural characteristics of different subtypes of interstitial cells of Cajal (ICC) remain unclear in birds; however, birds have significant economical and scientific notability. Our aim was to describe and classify ICC in the chicken gut. The ileum of normal adult Three Yellow broiler chickens (n=10) were studied by transmission electron microscopy (TEM). The ICC were spindle- or stellate-shaped with ramified cell processes. They had numerous mitochondria, abundant intermediate filaments, fusiform nuclei (oval or indented), with a dense band of peripheral heterochromatin, and formed close contacts by true gap junctions with each other and with neighboring smooth muscle cells (SMC). The ICC were in close contact with enteric nerves, but true gap junctions were not found between them. A new subtype of ICC located in the lamina propria mucosae has been discovered. Some of the ICC showed typical features of SMC, including a basal lamina, caveolae, and dense bodies. Lacking intermediate filaments and caveolae distinguished them from the fibroblast-like cells showing well-developed secretory organelles, including coated vesicles and a patchy basal lamina. The ultrastructural features and distribution of ICC in chicken intestine is similar to mammals. They may play similar key regulatory roles in gastrointestinal motility. The new subtype of ICC discovered in the lamina propria mucosae may play a role in the regulation of secretion and absorption.
影响因子：
29.4
作者：
Sanders, KM
通讯作者：
Sanders, KM
神经网络晚于卡哈尔一个世纪。
影响因子：
--
作者：
Jermakowicz,WalterJ;Casagrande,VivienA
通讯作者：
Casagrande,VivienA