Day napping and short night sleeping are associated with higher risk of diabetes in older adults.
Day napping and short night sleeping are associated with higher risk of diabetes in older adults.
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DOI：
10.2337/dc09-1143
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发表时间：
2010-01
期刊：
影响因子：
16.2
通讯作者：
Chen H
中科院分区：
文献类型：
--
作者：
Xu Q;Song Y;Hollenbeck A;Blair A;Schatzkin A;Chen H
研究白天小睡或夜间睡眠时间短是否与糖尿病的高风险有关。这是一项前瞻性研究，评估了1996-1997年美国国立卫生研究院（NIH）-美国退休人员协会饮食与健康研究的174，542名参与者中与2000年至2006年诊断的糖尿病（n = 10，143）相关的白天小睡和夜间睡眠时间。比值比（OR）和95% CI来自多变量logistic回归模型。白天小睡时间越长，患糖尿病的风险越高。校正潜在混杂因素后，与不午睡的个体相比，午睡时间<1小时的个体OR为1.23（95%CI 1.18-1.29），午睡时间≥1小时的个体OR为1.55（95%CI 1.45-1.66）（Ptrend < 0.0001）。夜间睡眠以7- 8h为参照，OR值<5 h为1.46（95% CI 1.31-1.63），5-6 h为1.11（1.06-1.16），≥9 h为1.11（0.99-1.24）。在这两项分析中，对BMI的额外调整仅适度减弱了相关性。进一步的分析显示小睡时间和睡眠时间对糖尿病有统计学显著的交互作用（P < 0.0001）。在没有午睡的参与者中，只有夜间睡眠时间短与糖尿病的发生率较高相关，而在午睡≥1小时的参与者中，长时间和短时间睡眠都与较高的风险相关。白天小睡和夜间睡眠时间短与糖尿病风险较高有关。睡眠时间和糖尿病之间的联系可能会被午睡习惯所改变。
To examine whether day napping or short night sleeping is associated with higher risk of diabetes. This was a prospective study of hours of day napping and night sleeping assessed in 1996–1997 in relation to diabetes diagnosed between 2000 and 2006 (n = 10,143) among 174,542 participants in the National Institutes of Health (NIH)-AARP Diet and Health Study. Odds ratios (ORs) and 95% CI were derived from multivariate logistic regression models. Longer day napping was associated with a higher risk of diabetes. After adjustment for potential confounders, ORs were 1.23 (95% CI 1.18–1.29) for those reporting <1 h and 1.55 (95% CI 1.45–1.66) for those reporting ≥1 h of napping compared with individuals who did not nap (Ptrend < 0.0001). For night sleeping, with 7–8 h as the referent, the OR was 1.46 (95% CI 1.31–1.63) for <5 h, 1.11 (1.06–1.16) for 5–6 h, and 1.11 (0.99–1.24) for ≥9 h. In both analyses, additional adjustment for BMI only modestly attenuated the associations. Further analysis showed a statistically significant interaction between hours of napping and sleeping on diabetes (Pinteraction < 0.0001). Among participants with no napping, only short night sleeping was associated with higher occurrence of diabetes, whereas among those with ≥1 h of napping, both long and short sleeping was associated with higher risk. Day napping and short night sleeping are associated with higher risk of diabetes. The association between sleep duration and diabetes may be modified by napping habit.
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影响因子：
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