EZH2 mediates ATO-induced apoptosis in acute myeloid leukemia cell lines through the Wnt signaling pathway

EZH2 mediates ATO-induced apoptosis in acute myeloid leukemia cell lines through the Wnt signaling pathway
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EZH2通过Wnt信号通路介导ATO诱导的急性髓系白血病细胞系凋亡

DOI:
10.1007/s13277-015-4463-2
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发表时间:
2016-05
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通讯作者:
张昊
张昊
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作者:
张昊

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在这项研究中,我们研究了 EZH2 通过 Wnt/β-catenin 信号通路介导急性髓系白血病 (AML) 细胞系中细胞凋亡和对三氧化二砷 (ATO) 化疗耐药的相关机制。自发性细胞凋亡的诱导
In this study, we examined the mechanisms associated with EZH2 mediation of apoptosis and chemoresistance to arsenic trioxide (ATO) in acute myeloid leukemia (AML) cell lines through the Wnt/β-catenin signaling pathway. The induction of spontaneous apopto
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