Approaches for determining cardiac bidomain conductivity values: progress and challenges.
Approaches for determining cardiac bidomain conductivity values: progress and challenges.
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DOI：
10.1007/s11517-020-02272-z
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发表时间：
2020-12
影响因子：
3.2
通讯作者：
Johnston PR
中科院分区：
文献类型：
--
作者：
Johnston BM;Johnston PR
心脏电活动建模是了解各种疾病和传导障碍中电功能的重要工具。显然，要使模型结果有用，就必须为模型，特别是常用的比多曼模型提供准确的输入。然而，只有三组实验确定的心室组织的四个电导率值，并且这些值是不一致的，是大约四十年前测量的，在模拟中经常产生不同的结果，并且不能完全代表心脏组织的三维各向异性性质。尽管在其间的几年中的努力，与进行测量，并确定从实验数据的电导率相关的困难尚未被克服。在这篇综述中，我们总结了什么是已知的电导率值，以及迄今为止在满足与数学建模和实验技术相关的挑战的进展。
Modelling the electrical activity of the heart is an important tool for understanding electrical function in various diseases and conduction disorders. Clearly, for model results to be useful, it is necessary to have accurate inputs for the models, in particular the commonly used bidomain model. However, there are only three sets of experimentally determined four conductivity values for cardiac ventricular tissue and these are inconsistent, were measured around forty years ago, often produce different results in simulations, and do not fully represent the three dimensional anisotropic nature of cardiac tissue. Despite efforts in the intervening years, difficulties associated with making the measurements and also determining the conductivities from the experimental data have not yet been overcome. In this review, we summarise what is known about the conductivity values, as well as progress to date in meeting the challenges associated with both the mathematical modelling and the experimental techniques.
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DOI：
10.1111/j.1540-8167.1993.tb01219.x
发表时间：
1993-04-01
影响因子：
2.7
作者：
COLLI-FRANZONE, P;GUERRI, L;TACCARDI, B
通讯作者：
TACCARDI, B
DOI：
10.1177/1179546816686061
发表时间：
2017
期刊：
Clinical Medicine Insights. Cardiology
影响因子：
--
作者：
Edwards AG;Louch WE
通讯作者：
Louch WE
影响因子：
4.6
作者：
Barr, RC;Plonsey, R
通讯作者：
Plonsey, R
DOI：
10.1098/rsta.2016.0289
发表时间：
2017-05-17
影响因子：
5
作者：
Boccia, E.;Luther, S.;Parlitz, U.
通讯作者：
Parlitz, U.
影响因子：
8.4
作者：
Caldwell, Bryan J.;Trew, Mark L.;Smaill, Bruce H.
通讯作者：
Smaill, Bruce H.