A Pilot Double Blind Randomized Placebo Controlled Trial of a Prototype Computer-Based Cognitive Behavioural Therapy Program for Adolescents with Symptoms of Depression
A Pilot Double Blind Randomized Placebo Controlled Trial of a Prototype Computer-Based Cognitive Behavioural Therapy Program for Adolescents with Symptoms of Depression
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针对有抑郁症状的青少年的基于计算机的原型认知行为治疗计划的双盲随机安慰剂对照试验
DOI：
10.1017/s1352465812001087
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发表时间：
2012
影响因子：
1.8
通讯作者：
S. Merry
中科院分区：
文献类型：
--
作者：
K. Stasiak;S. Hatcher;C. Frampton;S. Merry
背景：抑郁症在青少年中很常见，但大部分未得到治疗。计算机提供了一种增加获得护理的途径。计算机化治疗对成年人抑郁症有效，但迄今为止对青少年抑郁症的治疗还很少。目的：本研究的目的是检验计算机认知行为治疗（cCBT）项目“旅程”的可行性、可接受性和效果。方法：由学校辅导员介绍的34名青少年（平均年龄15.2岁，SD = 1.5）被随机分配到cCBT或计算机管理的心理教育内容（CPE）注意安慰剂计划。参与者在学校完成了干预。在基线、干预后和1个月随访时收集数据。主要结局指标为修订儿童抑郁评定量表（CDRS-R）；次要结局指标为：RADS-2；儿童生活质量量表；青少年应对量表（简表）；CDRS-R的缓解率。使用完成率和自我报告满意度来评估干预的可行性和可接受性。结果：94%的cCBT参与者和82%的CPE参与者完成了干预。89%的人非常喜欢《旅程》，或者认为它“还行”，89%的人会推荐它与其他人一起使用，或者在进行了一些改进后。cCBT治疗的青少年CDRS-R症状改善明显优于CPE治疗（cCBT平均变化= 17.6,CI = 14.13 ~ 21.00; CPE = 6.06, CI = 2.01 ~ 10.02, p< 0.001）。结论：在学校环境下对抑郁青少年进行计算机化CBT治疗是可行、可接受和有效的。通用性受到研究规模的限制。
Background: Depressive disorder is common in adolescents and largely untreated. Computers offer a way of increasing access to care. Computerized therapy is effective for depressed adults but to date little has been done for depressed adolescents. Aims: The objective of this study was to examine the feasibility, acceptability, and effects of The Journey, a computerized cognitive behavioural therapy (cCBT) program for depressed adolescents. Method: Thirty-four adolescents (mean age 15.2 years, SD = 1.5) referred by school counsellors were randomly assigned to either cCBT or a computer-administered attention placebo program with psychoeducational content (CPE). Participants completed the intervention at school. Data were collected at baseline, post-intervention and at a 1-month follow-up. The primary outcome measure was the Child Depression Rating Scale Revised (CDRS-R); secondary outcome measures were: RADS-2; Pediatric Quality of Life Inventory; Adolescent Coping Scale (short form); response and remission rates on CDRS-R. Completion rates and self-reported satisfaction ratings were used to assess feasibility and acceptabililty of the intervention. Results: Ninety-four percent of cCBT and 82% of CPE participants completed the intervention. Eighty-nine percent liked The Journey a lot or thought it was “okay” and 89% of them would recommend it for use with others as is or after some improvement. Adolescents treated with cCBT showed greater symptom improvement on CDRS-R than those treated with CPE program (mean change on cCBT = 17.6, CI = 14.13–21.00; CPE = 6.06, CI = 2.01–10.02; p< .001). Conclusions: It is feasible, acceptable and efficacious to deliver computerized CBT to depressed adolescents in a school setting. Generalizability is limited by the size of the study.
影响因子：
9.7
作者：
BURNS, BJ;COSTELLO, EJ;ERKANLI, A
通讯作者：
ERKANLI, A
影响因子：
4.6
作者：
LEWINSOHN, PM;HOPS, H;ANDREWS, JA
通讯作者：
ANDREWS, JA