Pro-Inflammatory Diets Are Associated with Frailty in an Urban Middle-Aged African American and White Cohort.
Pro-Inflammatory Diets Are Associated with Frailty in an Urban Middle-Aged African American and White Cohort.
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DOI：
10.3390/nu15214598
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发表时间：
2023-10-29
期刊：
影响因子：
5.9
通讯作者：
Zonderman AB
中科院分区：
文献类型：
--
作者：
Kuczmarski MF;Beydoun MA;Georgescu MF;Noren Hooten N;Mode NA;Evans MK;Zonderman AB
饮食质量是虚弱的一个可改变的危险因素，但关于虚弱与饮食炎症潜力之间关系的研究有限。目的是确定通过饮食炎症指数 (DII) 评估的饮食质量与随时间变化的虚弱状态之间的关联。使用来自纵向多元化社区健康老龄化 (HANDLS) 研究的饮食和虚弱数据的参与者（n = 2901，43.5% 男性，43.8% 非洲裔美国人，平均基线年龄 48.5 岁，平均随访时间 8.7 年）。基于组的轨迹模型确定了两个虚弱组（保持不虚弱或随着时间的推移处于虚弱前/虚弱状态）和三个饮食质量轨迹组（高或中等促炎和抗炎潜力）。多重 Logistic 回归发现，与高促炎组相比，中等促炎和抗炎 DII 轨迹组与整个样本（无论性别和种族）随时间推移的不虚弱呈正相关。 Kaplan-Meier 曲线和对数秩检验显示，抗炎 DII 评分与较低的预衰弱或衰弱风险相关。基线虚弱状态与年化 DII 变化之间不存在纵向关系，这是对反向因果关系的检查。这项研究为我们目前的知识做出了贡献，提供了抗炎 DII 评分与较低虚弱风险之间联系的纵向证据。
Diet quality is a modifiable risk factor for frailty, but research on the association of frailty with dietary inflammatory potential is limited. The objective was to determine associations between diet quality assessed by the dietary inflammatory index (DII) with frailty status over time. Participants with both dietary and frailty data from the longitudinal Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study were used (n = 2901, 43.5% male, 43.8% African American, 48.5 y mean baseline age, with a mean 8.7 y of follow-up). Group-based trajectory modeling identified two frailty (remaining non-frail or being pre-frail/frail over time) and three diet quality trajectory groups (high or medium pro-inflammatory and anti-inflammatory potentials). Multiple logistic regression found both medium pro-inflammatory and anti-inflammatory DII trajectory groups, compared to the high pro-inflammatory group, were positively associated with being non-frail over time for the overall sample, both sexes and races. Kaplan–Meier curves and log-rank test revealed anti-inflammatory DII scores were associated with lower risk for being pre-frail or frail. No longitudinal relationship existed between frailty status at baseline and annualized DII change, a check on reverse causality. This study contributes to our current knowledge providing longitudinal evidence of the link between anti-inflammatory DII score with lower frailty risk.
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影响因子：
5.9
作者：
Fanelli Kuczmarski M;Bodt BA;Stave Shupe E;Zonderman AB;Evans MK
通讯作者：
Evans MK
影响因子：
5.8
作者：
Kuczmarski, M. Fanelli;Pohlig, R. T.;Evans, M. K.
通讯作者：
Evans, M. K.
影响因子：
5.9
作者：
Fanelli Kuczmarski M;Sebastian RS;Goldman JD;Murayi T;Steinfeldt LC;Eosso JR;Moshfegh AJ;Zonderman AB;Evans MK
通讯作者：
Evans MK
DOI：
10.1016/j.jand.2017.02.010
发表时间：
2017-09-01
影响因子：
4.8
作者：
Kuczmarski, Marie Fanelli;Cotugna, Nancy;Zonderman, Alan B.
通讯作者：
Zonderman, Alan B.
DOI：
10.1007/s12603-012-0084-2
发表时间：
2012-07
期刊：
The journal of nutrition, health & aging
影响因子：
--
作者：
Morley JE;Malmstrom TK;Miller DK
通讯作者：
Miller DK