Efferent unmasking of speech-in-noise encoding?

Efferent unmasking of speech-in-noise encoding?
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噪声中语音编码的传出去掩蔽?

DOI:
10.1080/14992027.2020.1862425
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发表时间:
2021-09
影响因子:
2.7
通讯作者:
Cone B
Cone B
中科院分区:
医学3区
文献类型:
--
作者:
Smith SB;Cone B

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内侧耳蜗(MOC)反射提供脑干向耳蜗外毛细胞的传出反馈。生理学研究表明,MOC反射参与了听神经水平的噪声信号的“揭露”;然而,它在人类听力中的功能重要性尚不清楚。本研究考察了四种情况(安静、对侧噪声、同侧噪声和同侧+对侧噪声)下MOC反射强度(点击引起的耳声发射抑制;CEOAE)的神经前测量与噪声中语音编码(响应后语音频率;sFFR)的神经测量之间的关系。采用三种CEOAE抑制措施(幅度降低、有效衰减和输入-输出斜率抑制)来量化神经前MOC反射强度。评估了神经前MOC反射强度与sFFR“解除掩蔽”(即MOC反射在时域和频域激活后掩蔽效应的反应恢复)之间的相关性。18名听力正常的年轻人。sFFR揭开效果不显著,神经前MOC反射强度与sFFR揭开在时域和频域均无相关性。我们的研究结果不支持MOC反射参与噪声语音神经编码的假设,至少对于在信噪比测试中sFFR中表示的特征是如此。
The medial olivocochlear (MOC) reflex provides efferent feedback from the brainstem to cochlear outer hair cells. Physiologic studies have demonstrated that the MOC reflex is involved in “unmasking” of signals-in-noise at the level of the auditory nerve; however, its functional importance in human hearing remains unclear. This study examined relationships between pre-neural measurements of MOC reflex strength (click-evoked otoacoustic emission inhibition; CEOAE) and neural measurements of speech-in-noise encoding (speech frequency following response; sFFR) in four conditions (Quiet, Contralateral Noise, Ipsilateral Noise, and Ipsilateral + Contralateral Noise). Three measures of CEOAE inhibition (amplitude reduction, effective attenuation, and input-output slope inhibition) were used to quantify pre-neural MOC reflex strength. Correlations between pre-neural MOC reflex strength and sFFR “unmasking” (i.e., response recovery from masking effects with activation of the MOC reflex in time and frequency domains) were assessed. 18 young adults with normal hearing. sFFR unmasking effects were insignificant, and there were no correlations between pre-neural MOC reflex strength and sFFR unmasking in the time or frequency domain. Our results do not support the hypothesis that the MOC reflex is involved in speech-in-noise neural encoding, at least for features that are represented in the sFFR at the SNR tested.
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影响因子: 16.6
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