Identical ends are not required for the equal encapsidation of plus- and minus-strand parvovirus LuIII DNA
Identical ends are not required for the equal encapsidation of plus- and minus-strand parvovirus LuIII DNA
复制标题
正链和负链细小病毒 LuIII DNA 的相同衣壳不需要相同的末端
作者:
N. Diffoot;B. Shull;K. C. Chen;E. R. Stout;M. Lederman;R. Bates
Sequence analyses of the left and right termini of LuIII virus show they are nonidentical imperfect palindromes of 122 and 211 nucleotides, respectively. The left terminus of the minus strand of LuIII DNA, uniquely in the flip conformation, can assume a T-shaped structure. The right terminus of the minus strand of LuIII DNA can assume a U-shaped structure, and it exists in either the flip or flop conformation. The termini of LuIII shared a high degree of sequence homology and showed conserved secondary structure with those of the rodent parvoviruses MVMp and H-1. LuIII, like adeno-associated virus, encapsidates equal amounts of plus- and minus-strand DNA. However, the sequence data for LuIII virus demonstrate that identical termini are not required for this encapsidation pattern.
DOI:
10.1099/0022-1317-64-11-2527
发表时间:
1983
期刊:
The Journal of general virology
影响因子:
--
作者:
Summers,J;Jones,SE;Anderson,MJ
通讯作者:
Anderson,MJ