The relationship of serum immunoglobulin E to cigarette smoking.

The relationship of serum immunoglobulin E to cigarette smoking.
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血清免疫球蛋白E与吸烟的关系。

DOI:
10.1164/arrd.1981.124.5.523
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发表时间:
1981
期刊:
The American review of respiratory disease
影响因子:
--
通讯作者:
Lebowitz,MD
Lebowitz,MD
中科院分区:
--
文献类型:
--
作者:
Burrows,B;Halonen,M;Barbee,RA;Lebowitz,MD

文献摘要

参考文献

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在亚利桑那州图森市进行的一项普通人群研究中,来自成年人的数据表明,吸烟者的血清IgE浓度高于非吸烟者,尽管至少在35岁以后过敏皮肤试验反应性的比率较低。15岁后,过敏性皮肤试验阳性和皮肤试验阴性的非吸烟者血清IgE随年龄的增长而显著下降,但在相似的吸烟者组中没有显著的年龄下降。戒烟者戒烟后血清IgE浓度下降。此外,在春季非吸烟者中观察到的几何平均IgE显着增加在吸烟者中并未观察到。这些数据表明,吸烟直接或间接导致血清IgE升高,而且这种过量的IgE可能与非吸烟者的血清IgE有质的不同。对可能的作用机制进行了讨论。这些观察结果提出了一种可能性,即吸烟对健康的一些不利影响可能是免疫介导的。
Data from adults enrolled in a general population study in Tucson, Arizona, indicated that smokers have higher serum IgE concentrations than nonsmokers, despite a lower rate of allergy skin test reactivity, at least after 35 yr of age. After 15 yr of age there was a significant decline in serum IgE with age in both allergy skin test positive and skin test negative nonsmokers but no significant age decline was noted in similar groups of smokers. Ex-smokers showed a decline in serum IgE concentrations since quitting cigarettes. Also, the marked increase in geometric mean IgE that was seen in nonsmokers during the spring was not observed in smokers. The data suggested that smoking leads, directly or indirectly, to an increase in serum IgE and that this excess IgE may be qualitatively different from that seen in nonsmokers. Possible mechanisms for the effect are discussed. The observations raised the possibility that some of the adverse health effects of smoking might be immunologically mediated.
血清 IgE 水平:与皮试敏感性的相关性。
DOI: --
发表时间: 1973
期刊: Annals of allergy
影响因子: --
作者:
J. A. Loeffler;L. Cawley;M. Moeder
通讯作者: M. Moeder
血清和分泌物中 IgE 蛋白测量程序的比较。
DOI: --
发表时间: 1977
影响因子: 14.2
作者:
G. Gleich;S. Dunnette
通讯作者: S. Dunnette
DOI: --
发表时间: 1976
期刊: Clinical allergy
影响因子: --
作者:
S. Johansson;Asta Berglund;N. Kjellman
通讯作者: N. Kjellman