Recent Advances in Carbon Nanodots: A Promising Nanomaterial for Biomedical Applications.

Recent Advances in Carbon Nanodots: A Promising Nanomaterial for Biomedical Applications.
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碳纳米点的最新进展:一种有前途的生物医学应用纳米材料。

DOI:
10.3390/ijms22136786
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发表时间:
2021-06-24
影响因子:
5.6
通讯作者:
Jia Z
Jia Z
中科院分区:
生物学2区
文献类型:
--
作者:
Khan S;Dunphy A;Anike MS;Belperain S;Patel K;Chiu NHL;Jia Z

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碳纳米点(carbonnanodots,CND)是一类新兴的纳米材料,具有良好的生物相容性、稳定性、光致发光性、上级稳定性、简单的绿色合成和易于表面修饰等独特的性能,在生物医学领域引起了广泛的关注。CND已经在许多应用中发挥作用,包括生物成像、生物传感和治疗。本文综述了近几年来CND的研究进展,并讨论了CND在理解和作为生物医学工具的潜力方面的关键进展。我们强调了最近的发展,通过修改掺杂剂和表面分子,这已经产生了更深入的了解其抗氧化行为和作用机制的功能定制的CND的理解。关于CND的体外研究的增加也引起了对体内实践的兴趣。其中,我们讨论了研究分析CND作为有用的治疗药物在各种疾病状态的出现。每个主题都进行了辩论,并对未来的研究进行了反思,这些研究可能会进一步加深我们对CND的理解。
Carbon nanodots (CNDs) are an emerging class of nanomaterials and have generated much interest in the field of biomedicine by way of unique properties, such as superior biocompatibility, stability, excellent photoluminescence, simple green synthesis, and easy surface modification. CNDs have been featured in a host of applications, including bioimaging, biosensing, and therapy. In this review, we summarize the latest research progress of CNDs and discuss key advances in our comprehension of CNDs and their potential as biomedical tools. We highlighted the recent developments in the understanding of the functional tailoring of CNDs by modifying dopants and surface molecules, which have yielded a deeper understanding of their antioxidant behavior and mechanisms of action. The increasing amount of in vitro research regarding CNDs has also spawned interest in in vivo practices. Chief among them, we discuss the emergence of research analyzing CNDs as useful therapeutic agents in various disease states. Each subject is debated with reflection on future studies that may further our grasp of CNDs.
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