Community-based DOT-HAART accompaniment in an urban resource-poor setting.

Community-based DOT-HAART accompaniment in an urban resource-poor setting.
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DOI:
10.1007/s10461-009-9559-5
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发表时间:
2010-06
期刊:
影响因子:
4.4
通讯作者:
Shin S
Shin S
中科院分区:
医学2区
文献类型:
--
作者:
Muñoz M;Finnegan K;Zeladita J;Caldas A;Sanchez E;Callacna M;Rojas C;Arevalo J;Sebastian JL;Bonilla C;Bayona J;Shin S

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从2005年12月至2007年4月,我们在秘鲁利马的一个卫生区招募了60名开始抗逆转录病毒治疗(ART)的成年人,以接受基于社区的监督抗逆转录病毒治疗(CASA)。有偿社区卫生工作者每天进行两次家访,直接观察抗逆转录病毒疗法,并向CASA参与者提供额外的医疗、社会和经济支持。我们从邻近地区的年龄,CD 4和主要转诊标准(结核病状态,女性,两者都没有)匹配60名对照。在基线和12个月(DOT-HAART完成时间)使用有效的工具,我们测量了抑郁,社会支持,生活质量,艾滋病毒相关的耻辱和自我效能。我们比较了12个月的临床和心理社会结果之间的CASA与对照组。CASA参与者在12个月时经历了更好的临床和心理社会结果,包括病毒学抑制的比例,社会支持的增加和艾滋病毒相关污名的减少。
From December 2005 to April 2007, we enrolled 60 adults starting antiretroviral therapy (ART) in a health district of Lima, Peru to receive community-based accompaniment with supervised antiretroviral (CASA). Paid community health workers performed twice-daily home visits to directly observe ART and offered additional medical, social and economic support to CASA participants. We matched 60 controls from a neighboring district by age, CD4 and primary referral criteria (TB status, female, neither). Using validated instruments at baseline and 12 months (time of DOT-HAART completion) we measured depression, social support, quality of life, HIV-related stigma and self-efficacy. We compared 12 month clinical and psychosocial outcomes among CASA versus control groups. CASA participants experienced better clinical and psychosocial outcomes at 12 months, including proportion with virologic suppression, increase in social support and reduction in HIV-associated stigma.
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