Age-standardized mortality rates related to viral hepatitis in Brazil.
Age-standardized mortality rates related to viral hepatitis in Brazil.
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DOI：
10.1186/s12879-017-2619-y
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发表时间：
2017-07-31
影响因子：
3.7
通讯作者：
Veloso VG
中科院分区：
文献类型：
--
作者：
Perazzo H;Pacheco AG;Luz PM;Castro R;Hyde C;Fittipaldi J;Rigolon C;Cardoso SW;Grinsztejn B;Veloso VG
世界范围内与肝脏相关的死亡率一直在上升。我们的目的是估计巴西病毒性肝炎的年龄标准化死亡率。巴西国家死亡登记处从2008年到2014年进行了分析。病毒性肝炎死亡在死亡证明中按以下ICD-10代码定义：甲型肝炎[B15.0；B15.9];乙型肝炎[B16.2；B16.9;B18.1];丙型肝炎[B17.1；B18.2];丁型肝炎[B16.0；B16.1;B18.0;[B17.0]及其他病毒性肝炎[B17.2；B17.8;B18.8;B18.9;B19.0;B19.9]。粗死亡率由总死亡人数与估计人口之比计算。死亡率采用世卫组织标准人口直接法进行年龄标准化。34,978例死亡在死亡证明中提到病毒性肝炎[65%男性，58岁，73%与丙型肝炎相关]。病毒性肝炎年龄标准化死亡率（95% CI）为每10万居民2.695（2.667-2.724）例死亡，南方地区死亡率较高[3.997(3.911-4.085)]。甲型肝炎和丁型肝炎的死亡率分别为0.032（0.029-0.035）和0.028（0.025-0.031）。丙型肝炎死亡率是乙型肝炎相关死亡率的4倍[1.964（1.940-1.989）比0.500(0.488-0.512)]。南部地区丙型肝炎患病率较高[3.163(3.087-3.241)]，北部地区甲型肝炎患病率较高[0.066(0.049-0.087)]，乙型肝炎患病率较高[0.986(0.918-1.058)]，三角洲地区较高[0.220(0.190-0.253)]。病毒性肝炎仍然是巴西的一个主要公共卫生问题。全国各地的死亡率并不相同，这表明应根据地理位置制定卫生政策。本文的在线版本（doi:10.1186/s12879-017-2619-y）包含补充材料，授权用户可以使用。
Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil. The Brazilian National Death Registry was analyzed from 2008 to 2014. Viral hepatitis deaths were defined by the following ICD-10 codes in the death certificate: hepatitis A [B15.0; B15.9]; hepatitis B [B16.2; B16.9; B18.1]; hepatitis C [B17.1; B18.2]; hepatitis Delta [B16.0; B16.1; B18.0; B17.0] and other viral hepatitis [B17.2; B17.8; B18.8; B18.9; B19.0; B19.9]. Crude mortality rates were calculated by the ratio between total number of deaths and estimated population. Mortality rates were age-standardized by the direct method using the WHO standard population. Thirty four thousand ,nine hundred seventy eight deaths had viral hepatitis mentioned in their death certificate [65% male, aged 58 years, 73% associated with hepatitis C]. Age-standardized mortality rate (95% CI) due to viral hepatitis was 2.695 (2.667–2.724) deaths per 100,000 inhabitants: South region had the higher rates [3.997 (3.911–4.085)]. Mortality rates associated with hepatitis A and Delta were 0.032 (0.029–0.035) and 0.028 (0.025–0.031), respectively. Hepatitis C mortality rates were 4-fold higher than those associated with hepatitis B [1.964 (1.940–1.989) vs 0.500 (0.488–0.512)]. South region had the higher rates for hepatitis C [3.163 (3.087–3.241)] and North had the higher rates for hepatitis A [0.066 (0.049–0.087)], B [0.986 (0.918–1.058)] and Delta [0.220 (0.190–0.253)]. Viral hepatitis remains a major public health issue in Brazil. Mortality rates were not homogeneous across the country, suggesting that health policies should be customized according to geographical location. The online version of this article (doi:10.1186/s12879-017-2619-y) contains supplementary material, which is available to authorized users.
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影响因子：
0.6
作者：
da Rosa, Ligia;Dantas-Correa, Esther Buzaglo;Schiavon, Leonardo de Lucca
通讯作者：
Schiavon, Leonardo de Lucca
影响因子：
6.3
作者：
Barata RB;Ribeiro MC;de Moraes JC;Flannery B;Vaccine Coverage Survey 2007 Group
通讯作者：
Vaccine Coverage Survey 2007 Group
影响因子：
3.3
作者：
França E;Campos D;Guimarães MD;Souza Mde F
通讯作者：
Souza Mde F
影响因子：
168.9
作者：
Lozano, Rafael;Naghavi, Mohsen;Murray, Christopher J. L.
通讯作者：
Murray, Christopher J. L.
影响因子：
3.4
作者：
Ferreira, Paulo Roberto Abrão;Brandão-Mello, Carlos Eduardo;Mendes-Correa, Maria Cássia
通讯作者：
Mendes-Correa, Maria Cássia