Control of Arabidopsis root development.

Control of Arabidopsis root development.
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DOI:
10.1146/annurev-arplant-042811-105501
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发表时间:
2012
影响因子:
23.9
通讯作者:
Benfey PN
Benfey PN
中科院分区:
生物学1区
文献类型:
--
作者:
Petricka JJ;Winter CM;Benfey PN

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拟南芥根在过去几十年中一直是密集研究的主题。这项研究已经导致显着提高了对根发育的分子机制的理解。已经实现了对单个细胞类型、细胞模式、生长和分化、主根分支以及根对环境的响应的规范的关键见解。转录因子和植物激素起着关键的调节作用。最近,涉及蛋白质运动和基因表达振荡的机制也被发现。根基因调控网络控制根的发展已经重建从全基因组分析实验,揭示了新的分子连接和模型。未来这些模型的完善将导致一个更完整的描述复杂的分子相互作用,产生一个简单的增长的根。
The Arabidopsis root has been the subject of intense research over the past decades. This research has led to significantly improved understanding of the molecular mechanisms underlying root development. Key insights into the specification of individual cell types, cell patterning, growth and differentiation, branching of the primary root, and responses of the root to the environment have been achieved. Transcription factors and plant hormones play key regulatory roles. Recently, mechanisms involving protein movement and the oscillation of gene expression have also been uncovered. Root gene regulatory networks controlling root development have been reconstructed from genome-wide profiling experiments, revealing novel molecular connections and models. Future refinement of these models will lead to a more complete description of the complex molecular interactions that give rise to a simple growing root.
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