Interleukins in Thyroid Cancer: From Basic Researches to Applications in Clinical Practice
Interleukins in Thyroid Cancer: From Basic Researches to Applications in Clinical Practice
复制标题
白细胞介素在甲状腺癌中的作用:从基础研究到临床应用
DOI:
10.3389/fimmu.2020.01124
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发表时间:
2020-06
期刊:
影响因子:
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通讯作者:
Luo QY
中科院分区:
文献类型:
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作者:
Xi C;Zhang GQ;Sun ZK;Song HJ;Shen CT;Chen XY;Sun JW;Qiu ZL;Luo QY
Inflammation is crucial to tumorigenesis and progression of many cancers. Inflammatory molecules in tumor microenvironment exert pro- or anti-tumor effects. Among them, interleukin, mainly produced by CD3+ and CD4+ T lymphocytes, is a class of small molecule proteins which play an important role in intercellular communication. Numerous studies have confirmed that interleukins are closely related to thyroid cancer. Interleukins regulate the proliferation and migration of thyroid cancer cells and they have prospects in discriminating benign and malignant thyroid diseases, predicting the risk of tumorigenesis, evaluating the prognosis and monitoring the recurrence of thyroid cancer. Besides, the effective application of interleukins in treatment of thyroid cancer has been confirmed by some cell and animal researches. The present review will introduce the potential mechanisms of interleukins in thyroid cancer and focus on the applications of interleukins in clinical practice of thyroid cancer, which will help update understanding of the progress of interleukins researches in thyroid cancer.
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DOI:
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发表时间:
2017
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影响因子:
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作者:
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
通讯作者:
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
影响因子:
5.8
作者:
Durante, C.;Haddy, N.;Schlumberger, M.
通讯作者:
Schlumberger, M.
影响因子:
2.1
作者:
Kobawala TP;Trivedi TI;Gajjar KK;Patel DH;Patel GH;Ghosh NR
通讯作者:
Ghosh NR
影响因子:
32.4
作者:
Garlanda C;Dinarello CA;Mantovani A
通讯作者:
Mantovani A
DOI:
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发表时间:
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期刊:
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