Genome-wide studies of the transcriptional regulation by p53.
Genome-wide studies of the transcriptional regulation by p53.
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p53 转录调控的全基因组研究。
DOI:
10.1016/j.bbagrm.2012.02.002
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
Huang,Jing
中科院分区:
文献类型:
--
作者:
Li,Mangmang;He,Yunlong;Feng,Xi;Huang,Jing
The tumor suppressor p53 is arguably the most important transcription factor that safe-guards the genome. Although it is clear that the transcriptional activity of p53 is required for its tumor suppressive function, the underlying mechanisms are still largely unknown. In the past several years, genome-wide approaches have provided novel insights into the tumor suppressive functions of p53. This mini-review summarizes recent progress in studying these functions using genome-wide approaches, and offers some perspectives on this rapidly expanding field. This article is part of a Special Issue entitled: Chromatin in time and space.
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影响因子:
7
作者:
Dostie, Josee;Richmond, Todd A.;Dekker, Job
通讯作者:
Dekker, Job
DOI:
10.1039/c0ib00068j
发表时间:
2010-10
期刊:
Integrative biology : quantitative biosciences from nano to macro
影响因子:
--
作者:
Zhang X;Huang J
通讯作者:
Huang J
影响因子:
50.3
作者:
Jeffers, JR;Parganas, E;Zambetti, GP
通讯作者:
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56.9
作者:
Komarov, PG;Komarova, EA;Gudkov, AV
通讯作者:
Gudkov, AV
DOI:
10.1073/pnas.230445997
发表时间:
2000-11-21
影响因子:
11.1
作者:
Maxwell, SA;Davis, GE
通讯作者:
Davis, GE