The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria
The effect of intranasal desmopressin on nocturnal waking in urination in multiple system atrophy patients with nocturnal polyuria
复制标题
滴鼻去氨加压素对多系统萎缩伴夜间多尿患者夜醒排尿的影响
DOI：
10.1007/s10286-003-0052-3
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发表时间：
2003
影响因子：
5.8
通讯作者：
T. Hattori
中科院分区：
文献类型：
--
作者：
R. Sakakibara;S. Matsuda;T. Uchiyama;M. Yoshiyama;T. Yamanishi;T. Hattori
抽象的。夜间尿醒(夜尿症)是多系统萎缩(MSA)患者的常见特征。在这种疾病中，视交叉上核内精氨酸加压素(AVP)神经元的变性可能导致夜间多尿，这已经被肌肉内注射去氨加压素治疗。我们还对3例夜间多尿伴血浆加压素昼夜节律异常的多发性硬化患者开出5μg鼻腔去氨加压素，每晚1次。在治疗期间，所有患者的夜尿都有所改善，没有严重的不良反应。
Abstract. Nocturnal waking in urination (nocturia) is a common feature in patients with multiple system atrophy (MSA). Degeneration of arginine vasopressin (AVP) neurons in the suprachiasmatic nucleus in this disorder may lead to nocturnal polyuria, which has been treated with intramuscular desmopressin. We also prescribed 5 μg of intranasal desmopressin once a night in 3 MSA patients, who had nocturnal polyuria with abnormal circadian rhythm of the plasma AVP. During the treatment, all patients showed an improvement in their nocturia without serious adverse effects.
影响因子：
11
作者：
Sakakibara, R;Hattori, T;Yamanishi, T
通讯作者：
Yamanishi, T